Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15051368 | 0.89 | ALDH1A1 (0.43) | FDPSALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL8377299 | 0.84 | ALDH1A1 (0.58) | FDPSALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL28875403 | 0.82 | ALDH1A1 (0.59) | FDPSALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL30663744 | 0.82 | ALDH1A1 (0.59) | FDPSALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL28075459 | 0.81 | L3MBTL1 (0.46) | FDPSALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL8381920 | 0.81 | TNFRSF1A (0.47) | FDPSALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL5452274 | 0.80 | EGFR (0.41) | FDPSALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL4725328 | 0.80 | ALDH1A1 (0.47) | FDPSALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL1536736 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDHTTSMN1; SMN2NPC1 | |
| SCHEMBL8636872 | 0.78 | LMNA (0.46) | ALDH1A1TUBB1CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761672-B1 | Cephalosporins containing in position 7 a substituted benzyloxyimino radical, processes for their preparation and intermediates for their preparation, their use as medicaments | AVENTIS PHARMA SA (FR) | 2001-11-07 | — | — | EP | disclosed |
| US-5710147-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1998-01-20 | — | — | US | disclosed |
| EP-0761672-A1 | Cephalosporin containing in position 7 a substituted benzyloxyimino radical, processes for their preparation and intermediates for their preparation, their use as medicaments | ROUSSEL UCLAF (FR) | 1997-03-12 | — | — | EP | disclosed |