SCHEMBL8381981

SCHEMBL8381981

CC[SiH](c1ccccc1)[SiH](CC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
PSIP1 O75475 1/20 0.35
LMNA P02545 2/20 0.33
ALOX12 P18054 2/20 0.33
TSHR P16473 2/20 0.33
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
ACHE P22303 1/20 0.33
HIF1A Q16665 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
CYP2A6 P11509 2/20 0.32
ATM Q13315 1/20 0.32
CYP1A2 P05177 1/20 0.32
KCNN4 O15554 1/20 0.32
CALM1 P0DP23 1/20 0.32
MEN1 O00255 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9811043 0.85 TP53 (0.35) TP53PSIP1CALM1
SCHEMBL416585 0.77 TP53 (0.41) TP53PSIP1LMNAALOX12TSHR
SCHEMBL80927 0.77 TP53 (0.41) TP53PSIP1LMNAALOX12TSHR
SCHEMBL2229742 0.74 TP53 (0.39) TP53PSIP1LMNAALOX12TSHR
Water SCHEMBL20720558 0.74 TP53 (0.39) TP53PSIP1LMNAALOX12TSHR
Fluoride SCHEMBL27660896 0.74 TP53 (0.39) TP53PSIP1LMNAALOX12TSHR
Fluoride SCHEMBL27660670 0.74 TP53 (0.39) TP53PSIP1LMNAALOX12TSHR
SCHEMBL15302263 0.72 TP53 (0.38) TP53PSIP1LMNAALOX12TSHR
SCHEMBL9729956 0.72 TP53 (0.38) TP53PSIP1LMNAALOX12TSHR
SCHEMBL8384832 0.72 TP53 (0.38) TP53PSIP1LMNAALOX12TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630933-B1 A method of producing a semiconducting material NIPPON OIL CO LTD (JP) 1999-04-14 EP disclosed
US-5700400-A Method for producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1997-12-23 US disclosed
EP-0551771-B1 Process for producing polysilanes NIPPON OIL CO LTD (JP) 1997-07-30 EP disclosed
EP-0630933-A2 A method of producing a semiconducting material NIPPON OIL CO. LTD. (JP) 1994-12-28 EP disclosed
US-5304622-A Process for producing polysilanes NIPPON OIL COMPANY, LTD. (JP) 1994-04-19 US disclosed
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed