SCHEMBL416585

SCHEMBL416585

CC[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
PSIP1 O75475 1/20 0.35
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
TSHR P16473 3/20 0.33
LMNA P02545 2/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
ATM Q13315 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
KCNN4 O15554 1/20 0.32
CALM1 P0DP23 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31
LTA4H P09960 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27660670 0.97 TP53 (0.39) TP53PSIP1CES2CES1TSHR
SCHEMBL28998330 0.88 LMNA (0.43) TP53CES2CES1TSHRLMNA
SCHEMBL28339152 0.86 NFE2L2 (0.37) TP53TSHRLMNAACHECYP1A2
SCHEMBL6114431 0.78 TP53 (0.38) TP53PSIP1CES2CES1TSHR
SCHEMBL415335 0.78 TP53 (0.38) TP53PSIP1CES2CES1TSHR
SCHEMBL80927 0.77 TP53 (0.41) TP53PSIP1CES2CES1TSHR
SCHEMBL8381981 0.77 TP53 (0.41) TP53PSIP1CES2CES1TSHR
Fluoride SCHEMBL27660694 0.76 TP53 (0.36) TP53PSIP1CES2CES1LMNA
SCHEMBL706709 0.75 CALM1 (0.35) TP53TSHRLMNAALOX12ACHE
SCHEMBL704630 0.75 CALM1 (0.35) TP53TSHRLMNAALOX12ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 638 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118317992-A Dual UV blocker comprising a shelf-life stable photoactive bulk polymerized polycycloolefin composition as an optical material 普罗米鲁斯有限责任公司 2024-07-09 CN claimed
CN-115052914-B Shelf life-extended bulk polymerized polycycloolefin compositions as optical materials 住友电木株式会社 2023-06-30 CN claimed
CN-114938648-B Stable bulk polymerized polycycloolefin compositions as three-dimensional printing materials and methods of making same 住友电木株式会社 2023-06-30 CN claimed
CN-115052914-A Shelf life extended bulk polymerized polycycloolefin compositions as optical materials 普罗米鲁斯有限责任公司 2022-09-13 CN claimed
CN-114901711-A UV-active derivatives of Pd (AcAc) 2-catalyzed polycycloolefin compositions as optical materials 普罗米鲁斯有限责任公司 2022-08-12 CN claimed
CN-114901712-A AsPd (AcAc) of optical Material 2 UV active derivatives of L catalyzed polycycloolefin compositions 普罗米鲁斯有限责任公司 2022-08-12 CN claimed
CN-111943950-B Preparation method of rilibatan 山东安信制药有限公司 2022-03-29 CN claimed
CN-111656792-B Polycycloolefin monomers as optical materials and catalysts activated by compounds capable of generating photoacid 住友电木株式会社 2022-03-15 CN claimed
CN-110191903-B Polycycloolefinic polymer composition as optical material 住友电木株式会社 2021-08-06 CN claimed
CN-111943950-A Preparation method of rilibatan 山东安信制药有限公司 2020-11-17 CN claimed
EP-1002792-B1 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME MITSUBISHI PHARMA CORP (JP) 2004-07-14 EP claimed
CN-1130382-C Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST IND TECHNOLOGY (CN) 2003-12-10 CN claimed
CN-1324867-A Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST OF IND TECHN (CN) 2001-12-05 CN claimed
US-6313230-B1 HYDROGENATING CONJUGATED DIENE POLYMERS IN PRESENCE OF HYDROGEN AND A HYDROGENATION CATALYST FORMULATION COMPRISING TITANIUM COMPOUND, SILYL HYDRIDE COMPOUND, POLYSILOXANE, SILAZAN COMPOUND, AND METALLIC COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-11-06 US claimed
US-6214873-B1 PREVENTION OR SUPPRESION OF REJECTION OF ORGANS OR BONE MARROW TRANSPLANTATION; TREATMENT OF AUTOIMMUNE DISEASES OR ALLERGIC DISEASES; DECREASE IN TOXICITY AND HIGHER SAFETY WELFIDE CORPORATION (JP) 2001-04-10 US claimed
US-5756707-A REACTING A PARTIALLY PROTECTED CYTOSINE RIBONUCLEOSIDE WITH A HYDROCARBON HALIDE IN THE PRESENCE OF A METAL SALT CATALYST AND A BASE PERSEPTIVE BIOSYSTEMS, INC. (US) 1998-05-26 US claimed
WO-1996018638-A2 2'-O-DERIVATIZED PYRIMIDINE RIBONUCLEOSIDES AND METHODS OF PRODUCTION PERSEPTIVE BIOSYSTEMS, INC. (US) 1996-06-20 WO claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
US-5354340-A Preparation of copolymers SHELL OIL COMPANY (US) 1994-10-11 US claimed