Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19462005 | 0.89 | MAOA (0.67) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31441200 | 0.87 | RAB9A (0.68) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16226388 | 0.84 | MEN1 (0.60) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8382011 | 0.84 | MEN1 (0.84) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19462002 | 0.84 | MAOA (0.66) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL496978 | 0.82 | RAB9A (1.00) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10943501 | 0.81 | EPHX2 (0.63) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3190559 | 0.80 | MEN1 (0.58) | SMN1; SMN2MEN1KMT2AMAPTMAOA | |
| SCHEMBL12253692 | 0.80 | RAB9A (0.76) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3257870 | 0.79 | EPHX2 (0.62) | SMN1; SMN2MEN1KMT2AMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101426506-A | Novel anthraquinones and process for the preparation and method of use thereof | UNIV MICHIGAN (US) | 2009-05-06 | — | — | CN | claimed |
| EP-1745000-A2 | NOVEL ANTHRAQUINONES AND PROCESS FOR THE PREPARATION AND METHOD OF USE THEREOF | Michigan State University (US) | 2007-01-24 | — | — | EP | claimed |
| WO-2005113478-A2 | NOVEL ANTHRAQUINONES AND PROCESS FOR THE PREPARATION AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2005-12-01 | — | — | WO | claimed |
| EP-1745000-A2 | NOVEL ANTHRAQUINONES AND PROCESS FOR THE PREPARATION AND METHOD OF USE THEREOF | Michigan State University (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005113478-A2 | NOVEL ANTHRAQUINONES AND PROCESS FOR THE PREPARATION AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2005-12-01 | — | — | WO | disclosed |