Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.65 |
| ▸ | CTSS | P25774 | 2/20 | 0.65 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16946 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL9742302 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL21427213 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL7355314 | 0.87 | CTSK (0.67) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL9556128 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL16945 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL8283416 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL21427220 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL9742291 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL482062 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321166-A | Method for the production of aldehydes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-14 | — | — | US | claimed |
| EP-0559034-B1 | Process for the preparation of aldehydes | HOFFMANN LA ROCHE (CH) | 1999-04-14 | — | — | EP | disclosed |
| US-5321166-A | Method for the production of aldehydes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0559034-A2 | Process for the preparation of aldehydes | F. HOFFMANN-LA ROCHE AG (CH) | 1993-09-08 | — | — | EP | disclosed |