Sugi Predict

Sugi Predict / Compounds / SCHEMBL16945

SCHEMBL16945

SCHEMBL16945

CC(C)(C)OC(=O)NC(CC1CCCCC1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 5/20 0.70
▸ CTSS P25774 3/20 0.70
▸ AAK1 Q2M2I8 2/20 0.49
▸ HDAC4 P56524 1/20 0.48
▸ HDAC1 Q13547 1/20 0.48
▸ HDAC6 Q9UBN7 1/20 0.48
▸ GRN P28799 1/20 0.48
▸ SORT1 Q99523 1/20 0.48
▸ IDO1 P14902 1/20 0.46
▸ CPB2 Q96IY4 2/20 0.45
▸ CACNA1B Q00975 1/20 0.43
▸ REN P00797 2/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ EPHX1 P07099 1/20 0.43
▸ CTSL P07711 1/20 0.42
▸ CTSB P07858 1/20 0.42
▸ CTSH P09668 1/20 0.42
▸ PPARG P37231 1/20 0.41
▸ PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21427220 1.00 CTSK (0.70) CTSKCTSSAAK1HDAC4HDAC1
SCHEMBL9556128 1.00 CTSK (0.70) CTSKCTSSAAK1HDAC4HDAC1
SCHEMBL16946 1.00 CTSK (0.70) CTSKCTSSAAK1HDAC4HDAC1
SCHEMBL8283416 1.00 CTSK (0.70) CTSKCTSSAAK1HDAC4HDAC1
SCHEMBL9742291 1.00 CTSK (0.70) CTSKCTSSAAK1HDAC4HDAC1
SCHEMBL9742302 1.00 CTSK (0.70) CTSKCTSSAAK1HDAC4HDAC1
SCHEMBL482062 1.00 CTSK (0.70) CTSKCTSSAAK1HDAC4HDAC1
SCHEMBL21427213 1.00 CTSK (0.70) CTSKCTSSAAK1HDAC4HDAC1
Water SCHEMBL15646368 0.99 CTSK (0.73) CTSKCTSSAAK1HDAC4HDAC1
Water SCHEMBL266526 0.99 CTSK (0.73) CTSKCTSSAAK1HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480122-B Tetrahydroimidazo [1,2-a ] pyrazine compound, composition, preparation method and application thereof 中山大学 2022-03-22 — — CN claimed
US-4788322-A Process for preparing ACHPA MERCK & CO., INC. (US) 1988-11-29 — — US claimed
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS PARDES BIOSCIENCES INC (US) 2026-04-30 — — US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 — — US disclosed
US-20250122153-A1 Protease Inhibitors as Antivirals ACEA Therapeutics, Inc. (US) 2025-04-17 — — US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 — — EP disclosed
WO-2025034093-A1 PPM1D DEGRADATION-INDUCING COMPOUND AND USE THEREOF (주)노보메디슨 2025-02-13 — — WO disclosed
US-12145911-B2 Inhibitors of cysteine proteases and methods of use thereof Pardes Biosciences, Inc. (US) 2024-11-19 — — US disclosed
US-20240270721-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2024-08-15 — — US disclosed
US-20240270693-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2024-08-15 — — US disclosed
US-12060333-B2 Aminocarbamoyl compounds for the treatment of viral infections HOFFMANN-LA ROCHE INC. (US) 2024-08-13 — — US disclosed
EP-0452587-A1 Dihydroxy sulfonamide and sulfinamide renin inhibitors E.R. SQUIBB & SONS, INC. (US) 1991-10-23 — — EP disclosed
EP-0438233-A2 Orally active renin inhibitors PFIZER INC. (US) 1991-07-24 — — EP disclosed
US-4981843-A HYPOTENSIVE E. R. SQUIBB & SONS, INC. (US) 1991-01-01 — — US disclosed
US-4885292-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1989-12-05 — — US disclosed
EP-0337295-A2 Renin-inhibiting N-heterocyclic dipeptides E.R. Squibb & Sons, Inc. (US) 1989-10-18 — — EP disclosed
WO-1989007940-A1 1,2-HYDROXY PHOSPHONATES AND DERIVATIVES THEREOF E.R. SQUIBB & SONS, INC. (US) 1989-09-08 — — WO disclosed
EP-0331105-A2 1,2-Hydroxy phosphonates and derivatives thereof E.R. Squibb & Sons, Inc. (US) 1989-09-06 — — EP disclosed
EP-0306143-A1 Preparation of (3S,4S)-(N-alpha-boc)-4-amino-5-cyclohexyl-3-hydroxypentanoic-acid ethyl ester MERCK & CO. INC. (US) 1989-03-08 — — EP disclosed
US-4788322-A Process for preparing ACHPA MERCK & CO., INC. (US) 1988-11-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122153-A1 Protease Inhibitors as Antivirals ACE, ACE2, TMPRSS15 CTSK 86/4885CTSS 45/4885AAK1 2732/4885
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS CTRC, CTRL, CTSL CTSK 50/4885CTSS 7/4885AAK1 4588/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 CTSK 4661/4885CTSS 4022/4885AAK1 4583/4885
US-20240270693-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTRL, CTSV, CTSL CTSK 43/4885CTSS 7/4885AAK1 2433/4885
US-20240270721-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTSV, CTRL, CTSL CTSK 49/4885CTSS 10/4885AAK1 3082/4885
US-12060333-B2 Aminocarbamoyl compounds for the treatment of viral infections SARS1, BCAT1, SLC1A5 CTSK 2290/4885CTSS 1275/4885AAK1 3562/4885
US-12145911-B2 Inhibitors of cysteine proteases and methods of use thereof CTRL, CTSV, CTSL CTSK 43/4885CTSS 7/4885AAK1 2433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.