Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.70 |
| ▸ | CTSS | P25774 | 3/20 | 0.70 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | GRN | P28799 | 1/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21427220 | 1.00 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL9556128 | 1.00 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL8283416 | 1.00 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL9742291 | 1.00 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL9742302 | 1.00 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL482062 | 1.00 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL16945 | 1.00 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL21427213 | 1.00 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| Water SCHEMBL15646368 | 0.99 | CTSK (0.73) | CTSKCTSSAAK1HDAC4HDAC1 | |
| Water SCHEMBL266526 | 0.99 | CTSK (0.73) | CTSKCTSSAAK1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480122-B | Tetrahydroimidazo [1,2-a ] pyrazine compound, composition, preparation method and application thereof | 中山大学 | 2022-03-22 | — | — | CN | claimed |
| EP-0493087-B1 | Process for the crystallisation of N-t-butyloxycarbonyl-3-cyclohexyl-L-alanine methyl ester | AJINOMOTO KK (JP) | 1996-03-13 | — | — | EP | claimed |
| US-5286897-A | N-t-butyloxycarbonyl-3-cyclohexyl-L-alanine methyl ester in crystalline form | AJINOMOTO CO., INC. (JP) | 1994-02-15 | — | — | US | claimed |
| EP-0493087-A1 | Process for the crystallisation of N-t-butyloxycarbonyl-3-cyclohexyl-L-alanine methyl ester | Ajinomoto Co., Inc. (JP) | 1992-07-01 | — | — | EP | claimed |
| US-20260116857-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS | PARDES BIOSCIENCES INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260085092-A1 | MELANOCORTIN RECEPTOR LIGANDS | IPSEN PHARMA SAS (FR) | 2026-03-26 | — | — | US | disclosed |
| EP-4702033-A1 | DESMURAMYLPEPTIDE DIACIDS AS NOD2 AGONISTS AND USE THEREOF | Imhotex Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2025-07-29 | — | — | US | disclosed |
| EP-3303367-B1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-118845947-B | Preparation process of dendrobium candidum composite particles for clearing liver and improving eyesight | 江西省中医药研究院 | 2025-05-13 | — | — | CN | disclosed |
| CN-119930740-A | Dipeptide compound, chimeric molecule based on dipeptide compound and application of dipeptide compound | 西南交通大学 | 2025-05-06 | — | — | CN | disclosed |
| US-4885292-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0337295-A2 | Renin-inhibiting N-heterocyclic dipeptides | E.R. Squibb & Sons, Inc. (US) | 1989-10-18 | — | — | EP | disclosed |
| WO-1989007940-A1 | 1,2-HYDROXY PHOSPHONATES AND DERIVATIVES THEREOF | E.R. SQUIBB & SONS, INC. (US) | 1989-09-08 | — | — | WO | disclosed |
| EP-0331105-A2 | 1,2-Hydroxy phosphonates and derivatives thereof | E.R. Squibb & Sons, Inc. (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4603121-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1986-07-29 | — | — | US | disclosed |
| US-4514332-A | Tetrapeptide adamantyl amides | G. D. SEARLE & CO. (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0136720-A2 | Enkephalin analogs | G.D. Searle & Co. (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4495178-A | Enkephalin analogs | G. D. SEARLE & CO. (US) | 1985-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | CTSK 4487/4885CTSS 4120/4885AAK1 2876/4885 |
| US-20260116857-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS | CTRC, CTRL, CTSL | CTSK 50/4885CTSS 7/4885AAK1 4588/4885 |
| US-20260085092-A1 | MELANOCORTIN RECEPTOR LIGANDS | THRB, MC1R, MC5R | CTSK 4651/4885CTSS 4268/4885AAK1 1634/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | CTSK 4676/4885CTSS 4503/4885AAK1 3787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.