Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 14/20 | 0.62 |
| ▸ | MMP3 | P08254 | 10/20 | 0.62 |
| ▸ | MMP9 | P14780 | 6/20 | 0.59 |
| ▸ | MMP1 | P03956 | 4/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.59 |
| ▸ | ADAM9 | Q13443 | 2/20 | 0.59 |
| ▸ | AREG | P15514 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383874 | 0.89 | ALDH1A1 (0.51) | MMP8MMP3MMP9MMP1ADAM17 | |
| SCHEMBL27523317 | 0.89 | ALDH1A1 (0.51) | MMP8MMP3MMP9MMP1ADAM17 | |
| SCHEMBL208179 | 0.84 | MMP8 (0.80) | MMP8MMP3MMP1 | |
| SCHEMBL3495253 | 0.84 | MMP8 (0.80) | MMP8MMP3MMP1 | |
| SCHEMBL30627068 | 0.84 | MMP8 (0.80) | MMP8MMP3MMP1 | |
| SCHEMBL29697336 | 0.84 | MMP8 (0.80) | MMP8MMP3MMP1 | |
| SCHEMBL8382922 | 0.84 | MMP8 (0.49) | MMP8MMP3MMP9MMP1ADAM17 | |
| SCHEMBL8385012 | 0.75 | MMP9 (0.60) | MMP3MMP9MMP1ADAM17ADAM9 | |
| SCHEMBL10021369 | 0.75 | MMP9 (0.78) | MMP3MMP9MMP1ADAM17ADAM9 | |
| SCHEMBL10052772 | 0.73 | MMP9 (0.58) | MMP3MMP9MMP1ADAM17ADAM9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866587-A | HYDROXAMIDE DERIVATIVES OF FUSED PIPERIDINE DERIVATIVES | ADIR ET COMPAGNIE (FR) | 1999-02-02 | — | — | US | disclosed |