Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251635 | 0.87 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL24027122 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1CA1 | |
| SCHEMBL6632417 | 0.83 | MEN1 (0.62) | SIGMAR1ALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL15776693 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL5548988 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL25419509 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL7276024 | 0.81 | ITGB3 (0.43) | SIGMAR1ALDH1A1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL25001507 | 0.81 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL3569051 | 0.81 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL7278971 | 0.80 | ITGB3 (0.43) | SIGMAR1ALDH1A1SMN1; SMN2MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |