Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580703 | 0.92 | SIRT2 (0.48) | SIRT2KMT2AMEN1ATMPDE3B | |
| SCHEMBL29357152 | 0.92 | SIRT2 (0.48) | SIRT2KMT2AMEN1ATMPDE3B | |
| SCHEMBL28965595 | 0.90 | PDE3B (0.46) | KMT2AMEN1PDE3BPDE3AP2RY12 | |
| SCHEMBL28809220 | 0.88 | KMT2A (0.43) | KMT2AMEN1ATMPOLBMAOB | |
| SCHEMBL8379513 | 0.85 | KMT2A (0.48) | KMT2AMEN1ATMPOLBMAOB | |
| SCHEMBL4049950 | 0.82 | SIRT2 (0.40) | SIRT2KMT2AMEN1ATMPDE3B | |
| SCHEMBL12652439 | 0.82 | PDE3B (0.45) | ATMPDE3BPDE3AP2RY12POLB | |
| SCHEMBL15599733 | 0.81 | PDE3B (0.44) | KMT2AMEN1PDE3BPDE3AP2RY12 | |
| SCHEMBL4825877 | 0.81 | PDE3B (0.46) | KMT2AMEN1PDE3BPDE3AP2RY12 | |
| SCHEMBL294861 | 0.81 | PDE3B (0.46) | KMT2AMEN1PDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942626-A | REACTING A 5-HALO-SUBSTITUTED BENZOTRIAZOLE WITH A MERCAPTO COMPOUND IN THE PRESENCE OF A GROUP 1A METAL OR GROUP 2A COMPOUND FORMING 5-THIO-SUBSTITUTED 2H-BENZOTRIAZOLES HAVING ENHANCED ABSORBANCE AT LONGER WAVELENGTHS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-08-24 | — | — | US | disclosed |
| US-5849821-A | Tris-aryl-s-triazines substituted with biphenylyl groups | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |
| US-5844025-A | 1,2-Bis-adducts of stable nitroxides with substituted ethylenes and stabilized compositions | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-12-01 | — | — | US | disclosed |
| US-5844026-A | N,N',N''-tris{2,4-bis Hydrocarbyloxy-2,2,6,6-tetra-methylpiperidin-4-yl)alkylamino!-s-triazin-6-yl}-3,3'-ethylenediiminodipropylamines, their isomers and bridged derivatives and polymer compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-12-01 | — | — | US | disclosed |
| US-5726309-A | ULTRAVIOLET RADIATION ABSORBERS; THERMAL STABILIZERS FOR POLYMER SUBSTRATES, ESPECIALLY AUTOMOTIVE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |
| US-5684070-A | FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5681955-A | PHOTOSTABILITY OF POLYMERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-10-28 | — | — | US | disclosed |
| US-5679794-A | ACTINIC LIGHT RESISTANCE, PROCESSING HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |
| US-5675004-A | POLYMER STABILIZERS TO PROTECT AGAINST ACTINIC RADIATION COVERING MORE OF THE NEAR-UV SPECTRUM; DISCOLORATION INHIBITION; SYNERGISTIC EFFECT WITH HINDERED AMINES; ALKYD, ACRYLIC, URETHANE COATINGS | CIBA-GEIGY CORPORATION (US) | 1997-10-07 | — | — | US | disclosed |
| US-5512621-A | STABILIZER FOR POLYOLEFINS | CIBA-GEIGY CORPORATION (US) | 1996-04-30 | — | — | US | disclosed |