Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580703 | 0.89 | SIRT2 (0.48) | SIRT2KMT2AATMMEN1KDM4E | |
| SCHEMBL29357152 | 0.89 | SIRT2 (0.48) | SIRT2KMT2AATMMEN1KDM4E | |
| SCHEMBL12652439 | 0.86 | PDE3B (0.45) | ATMALDH1A1PDE3BPDE3AP2RY12 | |
| SCHEMBL8383100 | 0.82 | SIRT2 (0.46) | SIRT2KMT2AATMMEN1PDE3B | |
| SCHEMBL7125661 | 0.79 | L3MBTL1 (0.38) | KMT2AMEN1ALDH1A1KDM4ENPY1R | |
| SCHEMBL15599733 | 0.79 | PDE3B (0.44) | KMT2AMEN1KDM4EPDE3BPDE3A | |
| SCHEMBL294861 | 0.79 | PDE3B (0.46) | KMT2AMEN1KDM4EPDE3BPDE3A | |
| SCHEMBL4825877 | 0.79 | PDE3B (0.46) | KMT2AMEN1KDM4EPDE3BPDE3A | |
| SCHEMBL8383168 | 0.78 | HTT (0.43) | KMT2AMEN1ALDH1A1KDM4EPDE3B | |
| SCHEMBL30887231 | 0.78 | HTT (0.43) | KMT2AMEN1ALDH1A1KDM4EPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550599-B2 | Water compatible sterically hindered alkoxyamines and hydroxy substituted alkoxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-06-23 | — | — | US | disclosed |
| US-6585989-B2 | For use in plastic films, fibers and articles to provide antimicrobial activity, resistance to discoloration, may be processed at high temperature, and maintain physical properties upon weathering | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | disclosed |