SCHEMBL25504

SCHEMBL25504

Nc1ccccc1[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7346771 0.79 CD44 (0.42)
SCHEMBL8384 0.78 TSHR (0.35)
SCHEMBL10885088 0.77 CYP3A4 (0.36)
SCHEMBL7146499 0.77 NPC1 (0.67)
SCHEMBL1922269 0.77 CYP3A4 (0.76)
SCHEMBL3289851 0.75 MMP2 (0.47)
SCHEMBL7332288 0.75 CYP3A4 (0.56)
SCHEMBL9099850 0.75 ALDH1A1 (0.59)
SCHEMBL16099809 0.74 MAPT (0.55)
SCHEMBL157540 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2342 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
CN-117980327-A Specific coupling of antibodies 杭州多禧生物科技有限公司 2024-05-03 CN claimed
WO-2024074585-A2 MICROPARTICLE AND IMPLANT FORMULATIONS FOR cGMP ANALOG THERAPY MIRECA MEDICINES GMBH (DE) 2024-04-11 WO claimed
WO-2024040075-A1 EXTRACELLULAR VESICLE COMPRISING A BIOLOGICALLY ACTIVE MOLECULE AND A DUAL CLEAVABLE LINKER LONZA SALES AG (CH) 2024-02-22 WO claimed
US-11851697-B2 Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment GLYMPSE BIO, INC. (US) 2023-12-26 US claimed
EP-4267628-A1 ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES XL-protein GmbH (DE) 2023-11-01 EP claimed
CN-116854804-A Acylated oxyntomodulin peptide analogues 东亚ST株式会社 2023-10-10 CN claimed
WO-2023192417-A2 EX VIVO PROTEASE ACTIVITY DETECTION FOR HEPATOCELLULAR CARCINOMA GLYMPSE BIO, INC. (US) 2023-10-05 WO claimed
WO-2023172648-A2 FLUOROGENIC SUBSTRATES FOR AMINOPEPTIDASE DETECTION IN BIOFLUIDS GLYMPSE BIO, INC. (US) 2023-09-14 WO claimed
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2023-08-03 US claimed
US-4314936-A BY MEASUREM,ENT OF FLUORESENCE YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1982-02-09 US claimed
US-4269773-A CEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1981-05-26 US claimed
US-4232030-A ANTIBIOTICS MERCK & CO., INC. (US) 1980-11-04 US claimed
US-4226870-A ANTIBIOTICS, BACTERICIDES MERCK & CO., INC. (US) 1980-10-07 US claimed
EP-0001265-A1 O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds MERCK & CO. INC. (US) 1979-04-04 EP claimed
EP-0001264-A1 Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation MERCK & CO. INC. (US) 1979-04-04 EP claimed
US-4115378-A TEXTILES BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US claimed
US-4113431-A CELLULOSE REACTED WITH A BENZOYLATING AGENT SHIKIBO LIMITED (JP) 1978-09-12 US claimed
US-4002665-A Process for substituted cyclohexenes and its products WARNER-LAMBERT COMPANY (US) 1977-01-11 US claimed
US-3932393-A 3-Methylenecephalosporins and process for production thereof ELI LILLY AND COMPANY (US) 1976-01-13 US claimed