Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | USP8 | P40818 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29352197 | 0.85 | TSHR (0.63) | TSHRCA1CA2MCL1ALDH1A1 | |
| Water SCHEMBL19410621 | 0.85 | TSHR (0.63) | TSHRCA1CA2MCL1ALDH1A1 | |
| SCHEMBL57480 | 0.85 | TSHR (0.63) | TSHRCA1CA2MCL1ALDH1A1 | |
| SCHEMBL8384 | 0.85 | TSHR (0.35) | TSHRCA1CA2ALDH1A1HTT | |
| SCHEMBL2818597 | 0.85 | TSHR (0.63) | TSHRCA1CA2MCL1ALDH1A1 | |
| Water SCHEMBL27896186 | 0.85 | TSHR (0.63) | TSHRCA1CA2MCL1ALDH1A1 | |
| SCHEMBL28397671 | 0.83 | TSHR (0.50) | TSHRCA1CA2MCL1ALDH1A1 | |
| Formaldehyde SCHEMBL28231823 | 0.82 | TSHR (0.55) | TSHRCA1CA2MCL1ALDH1A1 | |
| SCHEMBL6372765 | 0.82 | TSHR (0.60) | TSHRCA1CA2MCL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8884007 | 0.82 | TSHR (0.60) | TSHRCA1CA2MCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3430022-B1 | COMPOUNDS AND METHODS FOR THE SYNTHESIS OF 5-(N-PROTECTED-TRYPTAMINOCARBOXYAMIDE)-2'-DEOXYURIDINE PHOSPHORAMIDITE FOR INCORPORATION INTO A NUCLEIC ACID SEQUENCE | SOMALOGIC INC (US) | 2020-03-11 | — | — | EP | claimed |
| CN-109796418-A | Phenylalanine derivative and the preparation method and application thereof containing 4- phenyl -1,2,3- triazole | 山东大学 | 2019-05-24 | — | — | CN | claimed |
| US-20190031702-A1 | Compounds and Methods for the Synthesis of 5-(N-Protected-Tryptaminocarboxyamide)-2'-Deoxyuridine Phosphoramidate for Incorporation into a Nucleic Sequence | SOMALOGIC, INC. (US) | 2019-01-31 | — | — | US | claimed |
| EP-3430022-A1 | COMPOUNDS AND METHODS FOR THE SYNTHESIS OF 5-(N-PROTECTED-TRYPTAMINOCARBOXYAMIDE)-2'-DEOXYURIDINE PHOSPHORAMIDATE FOR INCORPORATION INTO A NUCLEIC SEQUENCE | Somalogic, Inc. (US) | 2019-01-23 | — | — | EP | claimed |
| WO-2017160672-A1 | COMPOUNDS AND METHODS FOR THE SYNTHESIS OF 5-(N-PROTECTED-TRYPTAMINOCARBOXYAMIDE)-2'-DEOXYURIDINE PHOSPHORAMIDATE FOR INCORPORATION INTO A NUCLEIC SEQUENCE | SOMALOGIC, INC. (US) | 2017-09-21 | — | — | WO | claimed |
| US-20110184175-A1 | METHOD FOR PRODUCING BSH DERIVATIVE AND BSH DERIVATIVE | STELLA PHARMA CORPORATION (JP) | 2011-07-28 | — | — | US | claimed |
| EP-2319849-A1 | METHOD FOR PRODUCING BSH DERIVATIVE AND BSH DERIVATIVE | Stella Pharma Corporation (JP) | 2011-05-11 | — | — | EP | claimed |
| US-20100317653-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2010-12-16 | — | — | US | claimed |
| US-7741495-B2 | Indoline-sulfonamides compounds | TAIPEI MEDICAL UNIVERSITY (TW) | 2010-06-22 | — | — | US | claimed |
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PHOSPHOENIX SARL (FR) | 2010-04-22 | — | — | US | claimed |
| EP-0373663-A2 | Castanospermine esters in the inhibition of tumor metastasis | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-20 | — | — | EP | claimed |
| US-4754034-A | RECORDING MATERIALS, PRESSURE SENSITIVE, THERMOREACTIVE, ELECTROCHROMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-28 | — | — | US | claimed |
| EP-0180813-B1 | CHROMOGENIC 4,4-DIARYLDIHYDROCHINAZOLONES, THEIR PREPARATION AND USE | BAYER AG (DE) | 1988-06-01 | — | — | EP | claimed |
| US-4650868-A | 7-deazapurine derivatives useful as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-03-17 | — | — | US | claimed |
| EP-0180813-A1 | Chromogenic 4,4-diaryldihydrochinazolones, their preparation and use | BAYER AG (DE) | 1986-05-14 | — | — | EP | claimed |
| US-4571376-A | Color diffusion transfer photographic film unit with 1-M-(methyl or ethyl)phenyl-4-methyl-4-hydroxymethyl pyrazolidinones | FUJI PHOTO FILM CO., LTD. (JP) | 1986-02-18 | — | — | US | claimed |
| EP-0066378-B1 | PHARMACEUTICAL SPIRO-HYDANTOIN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-02 | — | — | EP | claimed |
| US-4386100-A | COMPLICATIONS OF DIABETES OR GALACTOSEMIA | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-05-31 | — | — | US | claimed |
| EP-0066378-A1 | Pharmaceutical spiro-hydantoin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-08 | — | — | EP | claimed |
| EP-0058932-A2 | 4-Aryloxy-1,2,3,4-tetrahydroisoquinolines, and intermediates, a process for preparing the same, a pharmaceutical composition containing the same and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-09-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317653-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | DGAT1, DGAT2, GPR119 | TSHR 1451/4885CA1 4775/4885CA2 4679/4885 |
| US-20110184175-A1 | METHOD FOR PRODUCING BSH DERIVATIVE AND BSH DERIVATIVE | CBS, DBH, CTH | TSHR 3831/4885CA1 3631/4885CA2 4451/4885 |
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PNP, NANP, PHOSPHO1 | TSHR 3165/4885CA1 1129/4885CA2 778/4885 |
| US-20190031702-A1 | Compounds and Methods for the Synthesis of 5-(N-Protected-Tryptaminocarboxyamide)-2'-Deoxyuridine Phosphoramidate for Incorporation into a Nucleic Sequence | TYMP, TYMS, NT5C2 | TSHR 2850/4885CA1 3796/4885CA2 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.