Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15831230 | 0.86 | MEN1 (0.62) | MEN1KMT2AHSD17B2BCHEACHE | |
| SCHEMBL14521710 | 0.77 | ROCK2 (0.53) | MEN1KMT2AHSD17B2BCHEACHE | |
| SCHEMBL6417242 | 0.75 | HSD17B2 (0.63) | MEN1KMT2AHSD17B2BCHEACHE | |
| SCHEMBL9781367 | 0.74 | ROCK2 (0.53) | MEN1KMT2AHSD17B2BCHEACHE | |
| SCHEMBL3996160 | 0.74 | HSD17B2 (0.61) | MEN1KMT2AHSD17B2BCHEACHE | |
| SCHEMBL850832 | 0.73 | CALM1 (0.64) | MEN1KMT2AHSD17B2BCHEACHE | |
| SCHEMBL29547354 | 0.73 | CALM1 (0.64) | MEN1KMT2AHSD17B2BCHEACHE | |
| SCHEMBL1134084 | 0.73 | KMT2A (0.61) | MEN1KMT2AHSD17B2BCHEACHE | |
| SCHEMBL9681681 | 0.73 | TAAR1 (0.56) | MEN1KMT2AHSD17B2TAAR1ALDH1A1 | |
| SCHEMBL3175855 | 0.73 | CTBP2 (0.57) | MEN1KMT2ATAAR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977132-A | GALACTORRHEA, HYPERPROLACTINEMIC OVULATION, PROLACTINOMA AND BRAIN TUMORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-02 | — | — | US | disclosed |