Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 3/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CLPP | Q16740 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497600 | 0.85 | GRN (0.54) | GRNSORT1MMECLPPCA2 | |
| SCHEMBL12984129 | 0.85 | CA2 (0.46) | MMECA2CA1 | |
| SCHEMBL9829475 | 0.84 | KDM4E (0.59) | GRNSORT1MMECLPPCA2 | |
| SCHEMBL9829479 | 0.84 | KDM4E (0.59) | GRNSORT1MMECLPPCA2 | |
| SCHEMBL23638345 | 0.82 | KDM4E (0.60) | GRNSORT1MMECLPPCA2 | |
| SCHEMBL2669218 | 0.82 | KDM4E (0.60) | GRNSORT1MMECLPPCA2 | |
| SCHEMBL12984512 | 0.81 | KDM4E (0.45) | TDP1CA2CA1PYGL | |
| SCHEMBL24344002 | 0.81 | GRN (0.51) | GRNSORT1MMECLPPCA2 | |
| SCHEMBL6244622 | 0.80 | CASP1 (0.57) | GRNSORT1FNTAFNTBPGGT1B | |
| SCHEMBL2334402 | 0.80 | UTS2R (0.42) | CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143052-B2 | Process for preparing optically active (S or R)-α amino acid and (R or S)-α amino acid ester in one phase organic reaction medium | UBE INDUSTRIES, LTD. (JP) | 2012-03-27 | — | — | US | disclosed |