Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | GRN | P28799 | 3/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | CLPP | Q16740 | 2/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829479 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8897190 | 0.90 | CA2 (0.52) | ALDH1A1CA2CA1GRNSORT1 | |
| SCHEMBL15242488 | 0.87 | HPGDS (0.54) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL30497600 | 0.86 | GRN (0.54) | CA2CA1GRNSORT1MME | |
| SCHEMBL5803352 | 0.84 | KDM4E (0.66) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL23638345 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1CA2CA1GRN | |
| SCHEMBL2669218 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1CA2CA1GRN | |
| SCHEMBL838494 | 0.84 | GRN (0.52) | CA2CA1GRNSORT1MME | |
| SCHEMBL12983737 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL24344002 | 0.82 | GRN (0.51) | CA2CA1GRNSORT1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |