⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28117319 | 0.86 | HIF1A (0.39) | — | |
| SCHEMBL27974503 | 0.84 | TBXAS1 (0.40) | — | |
| SCHEMBL28117796 | 0.82 | TBXAS1 (0.42) | — | |
| SCHEMBL28267625 | 0.82 | TBXAS1 (0.42) | — | |
| SCHEMBL28017293 | 0.82 | TBXAS1 (0.42) | — | |
| SCHEMBL27402335 | 0.80 | — | — | |
| SCHEMBL28365989 | 0.78 | — | — | |
| SCHEMBL2193910 | 0.78 | LMNA (0.50) | — | |
| SCHEMBL27670416 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL7841090 | 0.76 | ENPEP (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875557-B | Thiazole derivative and synthesis method thereof | 南通大学 | 2023-06-02 | — | — | CN | claimed |
| EP-0399755-B1 | Light-sensitive composition and presensitized plate for use in making lithographic printing plates | FUJI PHOTO FILM CO LTD (JP) | 1994-03-30 | — | — | EP | claimed |
| US-5112743-A | Aromatic-aldehyde diazo resins | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-12 | — | — | US | claimed |
| EP-0399755-A1 | Light-sensitive composition and presensitized plate for use in making lithographic printing plates | Fuji Photo Film Co., Ltd. (JP) | 1990-11-28 | — | — | EP | claimed |
| CN-118324633-A | Method for preparing ethyl 2-chloro-3-oxopropionate | 海门瑞一医药科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-111875557-B | Thiazole derivative and synthesis method thereof | 南通大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-103889563-B | Composite polyamide membranes derived from carboxylic acid-containing acyl halide monomers | 陶氏环球技术有限责任公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-103328088-B | Method for solubilizing carboxylic acid-containing compounds in hydrocarbon solvents | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-02-03 | — | — | CN | disclosed |
| CN-103906741-A | Aminoalkyl substituted N-thienylbenzamide derivatives | ASTELLAS PHARMA INC | 2014-07-02 | — | — | CN | disclosed |
| CN-103906509-A | Enkephalinase inhibitors | THERAVANCE INC | 2014-07-02 | — | — | CN | disclosed |
| CN-103889563-A | Composite polyamide membranes derived from carboxylic acid-containing acyl halide monomers | DOW GLOBAL TECHNOLOGIES INC | 2014-06-25 | — | — | CN | disclosed |
| CN-101180299-B | Ethynyl-pyrazolopyrimidine derivatives as MGLUR2 antagonists | HOFFMANN LA ROCHE | 2010-12-15 | — | — | CN | disclosed |
| CN-101410397-A | Organic compounds | NOVARTIS AG (CH) | 2009-04-15 | — | — | CN | disclosed |
| CN-101180299-A | Ethynyl-pyrazolopyrimidine derivatives as MGLUR2 antagonists | HOFFMANN LA ROCHE (CH) | 2008-05-14 | — | — | CN | disclosed |
| EP-0487343-B1 | Process for preparing a lithographic plate | FUJI PHOTO FILM CO LTD (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0399755-B1 | Light-sensitive composition and presensitized plate for use in making lithographic printing plates | FUJI PHOTO FILM CO LTD (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0487343-A1 | Process for preparing a lithographic plate | Fuji Photo Film Co., Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-5112743-A | Aromatic-aldehyde diazo resins | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0399755-A1 | Light-sensitive composition and presensitized plate for use in making lithographic printing plates | Fuji Photo Film Co., Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |