Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531168 | 0.89 | ADRA1A (0.61) | ADRA1APDE4DALDH1A1 | |
| SCHEMBL11035882 | 0.83 | ADRA1A (0.50) | ADRA1APDE4DALDH1A1KDM4EMAPT | |
| SCHEMBL2725876 | 0.79 | ADRA1A (0.46) | ADRA1APDE4D | |
| SCHEMBL8055886 | 0.79 | ADRA1A (0.82) | ADRA1APDE4DTSHR | |
| SCHEMBL9675143 | 0.77 | ADRA1A (0.44) | ADRA1APDE4D | |
| SCHEMBL9745261 | 0.77 | ADRA1A (0.45) | ADRA1APDE4D | |
| SCHEMBL9745480 | 0.77 | ADRA1A (0.45) | ADRA1APDE4D | |
| SCHEMBL9673550 | 0.76 | ADRA1A (0.47) | ADRA1APDE4D | |
| Water SCHEMBL9745436 | 0.75 | ADRA1A (0.43) | ADRA1APDE4D | |
| SCHEMBL11700838 | 0.73 | ADRA1A (0.53) | ADRA1APDE4DTSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962509-A | ANTIDIABETIC AGENTS | SSP CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0909758-A1 | Dithiolylidene acetamide derivatives | SSP Co., Ltd. (JP) | 1999-04-21 | — | — | EP | disclosed |
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1992-08-26 | — | — | EP | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0298040-A1 | 1,3-Dithiol-2-ylidene derivatives | YUHAN CORPORATION, LTD. (KR) | 1989-01-04 | — | — | EP | disclosed |