Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531168 | 0.89 | ADRA1A (0.61) | ADRA1APDE4DALDH1A1 | |
| SCHEMBL8385459 | 0.83 | ADRA1A (0.50) | ADRA1APDE4DALDH1A1MAPTKDM4E | |
| SCHEMBL9665862 | 0.82 | ADRA1A (0.50) | ADRA1APDE4DMAPT | |
| SCHEMBL9673550 | 0.76 | ADRA1A (0.47) | ADRA1APDE4D | |
| SCHEMBL11700838 | 0.73 | ADRA1A (0.53) | ADRA1APDE4DALDH1A1MAPTMEN1 | |
| SCHEMBL9672783 | 0.72 | ADRA1A (0.44) | ADRA1APDE4DALDH1A1MAPTMEN1 | |
| SCHEMBL28696790 | 0.71 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2A | |
| SCHEMBL9663808 | 0.70 | CES2 (0.56) | MAPTMEN1KMT2ACYP2C19 | |
| SCHEMBL10498540 | 0.68 | ADRA1A (0.39) | ADRA1APDE4D | |
| Malotilate SCHEMBL635496 | 0.67 | ADRA1A (1.00) | ADRA1APDE4DMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59042377-A | — | — | None | — | — | JP | disclosed |
| JP-S5942377-A | DITHIOL DERIVATIVE | NIPPON NOHYAKU CO LTD | 1984-03-08 | — | — | JP | disclosed |