SCHEMBL838588

SCHEMBL838588

Clc1cccc([I+]c2cccc(Cl)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
HTR3E A5X5Y0 1/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
HTR3B O95264 1/20 0.41
PLAU P00749 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
PNMT P11086 1/20 0.41
HTR2A P28223 2/20 0.39
HTR2C P28335 2/20 0.39
HTR2B P41595 2/20 0.39
CHRM5 P08912 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MCL1 Q07820 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31519530 1.00 ALDH1A1 (0.46) ALDH1A1TSHRHTR3ESLC22A2SLC22A1
SCHEMBL10827293 0.93 TSHR (0.46) ALDH1A1TSHRHTR3ESLC22A2SLC22A1
SCHEMBL2898174 0.91 ALDH1A1 (0.39) ALDH1A1TSHRHTR3ESLC22A2SLC22A1
SCHEMBL92061 0.80 LMNA (0.40) TSHRHTR2AHTR2CHTR2BMEN1
Hydrochloric Acid SCHEMBL192766 0.77 RAB9A (0.36) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL28129975 0.75 TSHR (0.61) ALDH1A1TSHRHTR3ESLC22A2SLC22A1
SCHEMBL28140 0.75
SCHEMBL15327483 0.72 TAAR1 (0.44) ALDH1A1TSHRHTR2AHTR2CHTR2B
Hydrogen Sulfide SCHEMBL22129212 0.72
Ammonia Solution, Strong SCHEMBL2163448 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230213858-A1 MANUFACTURING METHOD FOR CURED SUBSTANCE, MANUFACTURING METHOD FOR LAMINATE, AND MANUFACTURING METHOD FOR SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2023-07-06 US disclosed
US-20220171285-A1 METHOD OF MANUFACTURING CURED FILM, PHOTOCURABLE RESIN COMPOSITION, METHOD OF MANUFACTURING LAMINATE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2022-06-02 US disclosed
EP-1975707-B1 Curable composition and planographic printing plate precursor FUJIFILM CORP (JP) 2017-07-19 EP disclosed
US-8426102-B2 Lithographic printing plate precursor and plate making method FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-8309294-B2 2012-11-13 US disclosed
US-20120227605-A1 ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE, LITHOGRAPHIC PRINTING PLATE SUPPORT, PRESENSITIZED PLATE, METHOD OF MANUFACTURING ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE AND METHOD OF MANUFACTURING LITHOGRAPHIC PRINTING PLATE SUPPORT FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-8221957-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
US-8182980-B2 Good in developability, staining resistance and dispersibility of photosensitive layer in the developing solution FUJIFILM CORPORATION (JP) 2012-05-22 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20070259916-A1 mGluR5 modulators II ASTRAZENECA AB (SE) 2007-11-08 US disclosed
US-20070259926-A1 mGluR5 modulators III ASTRAZENECA AB (SE) 2007-11-08 US disclosed
US-20070259862-A1 MGluR5 modulators I ASTRAZENECA AB (SE) 2007-11-08 US disclosed
US-7291443-B2 Polymerizable composition and image-recording material using the same FUJIFILM CORPORATION (JP) 2007-11-06 US disclosed
US-20070224535-A1 Image Forming Method, Planographic Printing Plate Precursor, and Planographic Printing Method FUJIFILM CORPORATION (JP) 2007-09-27 US disclosed
US-20070212643-A1 Compound having polymethine-chain structure, image forming material, planographic printing plate precursor, and image forming method using the same, method of making planographic printing plate, and planographic printing method FUJIFILM CORPORATION 2007-09-13 US disclosed
US-20070202443-A1 Method for processing lithographic printing plate precursor, plate inspection method, image quality control method and dyeing aqueous solution used therein FUJIFILM CORPORATION 2007-08-30 US disclosed
US-7244546-B2 Planographic printing method and planographic printing plate precursor used therein FUJIFILM CORPORATION (JP) 2007-07-17 US disclosed
US-20070056457-A1 Lithographic printing plate precursor, lithographic printing method, and novel cyanine dye FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
US-20070037816-A1 Bicyclic piperazines as metabotropic glutatmate receptor antagonists ASTRAZENECA AB (SE) 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259862-A1 MGluR5 modulators I GRM5, GRM1, GRIK5 ALDH1A1 4350/4885TSHR 1225/4885HTR3E 190/4885
US-20070259926-A1 mGluR5 modulators III GRM5, GRM3, GRIK5 ALDH1A1 4536/4885TSHR 1201/4885HTR3E 89/4885
US-20070259916-A1 mGluR5 modulators II GRM5, GRM2, GRIK5 ALDH1A1 4552/4885TSHR 1270/4885HTR3E 214/4885
US-20070037816-A1 Bicyclic piperazines as metabotropic glutatmate receptor antagonists GRM5, GRM1, GRIN1 ALDH1A1 769/4885TSHR 998/4885HTR3E 345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.