Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129745 | 0.86 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL27532891 | 0.81 | KMT2A (0.51) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL6651845 | 0.78 | CYP4F2 (0.61) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6676119 | 0.76 | CYP4F2 (0.48) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL22067604 | 0.76 | MEN1 (0.56) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL5098387 | 0.75 | CYP3A4 (0.49) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL6660186 | 0.75 | CYP3A4 (0.51) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4564017 | 0.75 | CYP3A4 (0.51) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27362136 | 0.75 | CYP3A4 (0.51) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL157805 | 0.74 | CYP3A4 (0.61) | RAB9ANPC1MAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939437-A | AMIDE COMPOUNDS AS NEUROPEPTIDES AS APPETITE REGULATORS, ANXIOLYTIC ACTIVITY AND ANTICARCINOGENIC AGENTS | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-08-17 | — | — | US | disclosed |