SCHEMBL8386196

SCHEMBL8386196

CCCN([N]C(C)=O)C(C)=O

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8386139 0.80 ALDH1A1 (0.35) CA12CA2CA9TSHRALDH1A1
SCHEMBL8382707 0.80 CHRM1 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL103889 0.78
SCHEMBL8386109 0.77 ALDH1A1 (0.47) ALDH1A1HPGD
SCHEMBL483128 0.66 CA12 (0.55) CA12CA2CA9TSHRMAPK1
SCHEMBL11408090 0.66 CA12 (0.42) CA12CA2CA9TSHRMAPK1
SCHEMBL8383109 0.66 ALDH1A1 (0.48) TSHRALDH1A1
SCHEMBL103667 0.65 CA12 (0.40) CA12CA9ALDH1A1
SCHEMBL5136363 0.64
Hydrochloric Acid SCHEMBL3020939 0.64 CA12 (0.52) CA12CA2CA9TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5892109-A EXTRACTION FROM FERMENTATION BROTH USING TRIALKYLAMINE IN PRESENCE OF CARBON DIOXIDE CARGILL, INCORPORATED (US) 1999-04-06 US disclosed
US-4814060-A POLYVINYL CHLORIDE AND IONOPHORE NALCO CHEMICAL COMPANY (US) 1989-03-21 US disclosed