Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | PPARD | Q03181 | 3/20 | 0.31 |
| ▸ | PPARA | Q07869 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386109 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CES1LMNACES2TP53 | |
| SCHEMBL8381418 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CES1LMNACES2TP53 | |
| SCHEMBL8386139 | 0.73 | ALDH1A1 (0.35) | ALDH1A1CES1CES2TP53TSHR | |
| SCHEMBL103879 | 0.69 | ALDH1A1 (0.50) | ALDH1A1CES1LMNACES2TP53 | |
| SCHEMBL633207 | 0.69 | LMNA (0.80) | ALDH1A1CES1LMNACES2TP53 | |
| SCHEMBL8046344 | 0.67 | ALDH1A1 (0.65) | ALDH1A1CES1LMNACES2TP53 | |
| SCHEMBL827843 | 0.66 | — | — | |
| SCHEMBL9210592 | 0.66 | — | — | |
| SCHEMBL12522012 | 0.66 | ALDH1A1 (0.71) | ALDH1A1CES1LMNACES2TP53 | |
| SCHEMBL9838542 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |