Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 10/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386139 | 0.88 | ALDH1A1 (0.35) | ALDH1A1CES1CES2TP53HPGD | |
| SCHEMBL8383109 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CES1CES2TP53CA1 | |
| SCHEMBL103879 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CES1CES2TP53CA1 | |
| SCHEMBL8386196 | 0.77 | CA12 (0.34) | ALDH1A1HPGD | |
| SCHEMBL8381418 | 0.76 | ALDH1A1 (0.56) | ALDH1A1CES1CES2TP53CA1 | |
| SCHEMBL11770064 | 0.70 | ALDH1A1 (0.61) | ALDH1A1CES1CES2TP53CA1 | |
| SCHEMBL21710075 | 0.69 | ALDH1A1 (0.62) | ALDH1A1CES1CES2TP53CA1 | |
| SCHEMBL102978 | 0.67 | ALDH1A1 (0.38) | ALDH1A1CES1CES2TP53LMNA | |
| SCHEMBL12209586 | 0.67 | LMNA (0.62) | ALDH1A1CES1CES2TP53CA1 | |
| SCHEMBL27412205 | 0.67 | ALDH1A1 (0.54) | ALDH1A1CES1CES2TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | claimed |