SCHEMBL838630

SCHEMBL838630

O[C@H]1CCC[C@@H]2CCCCC21

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46
ALDH1A1 P00352 1/20 0.39
SLC18A3 Q16572 3/20 0.38
TSHR P16473 1/20 0.35
CTDSP1 Q9GZU7 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
KDM4E B2RXH2 1/20 0.31
APOBEC3A P31941 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3038819 1.00 CA1 (0.46) CA1CA2CA4ALDH1A1SLC18A3
SCHEMBL4613757 1.00 CA1 (0.46) CA1CA2CA4ALDH1A1SLC18A3
SCHEMBL21757863 1.00 CA1 (0.46) CA1CA2CA4ALDH1A1SLC18A3
SCHEMBL7733797 1.00 CA1 (0.46) CA1CA2CA4ALDH1A1SLC18A3
SCHEMBL8161261 1.00 CA1 (0.46) CA1CA2CA4ALDH1A1SLC18A3
SCHEMBL712232 1.00 CA1 (0.46) CA1CA2CA4ALDH1A1SLC18A3
SCHEMBL13767450 1.00 CA1 (0.46) CA1CA2CA4ALDH1A1SLC18A3
SCHEMBL23240064 0.97 CA1 (0.43) CA1CA2CA4ALDH1A1SLC18A3
SCHEMBL15178081 0.97 CA1 (0.43) CA1CA2CA4ALDH1A1SLC18A3
Methane SCHEMBL22471700 0.97 CA1 (0.43) CA1CA2CA4ALDH1A1SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115169-B2 Method of treating tumors LYTIX BIOPHARMA AS (NO) 2015-08-25 US disclosed
US-9109048-B2 Inhibition of tumor growth LYTIX BIOPHARMA AS (NO) 2015-08-18 US disclosed
US-20140037657-A1 INHIBITION OF TUMOR GROWTH LYTIX BIOPHARMA AS (NO) 2014-02-06 US disclosed
US-8283315-B2 Inhibition of tumour growth LYTIX BIOPHARMA AS (NO) 2012-10-09 US disclosed
US-20120108520-A1 Antimicrobial Compounds and Formulations LYTIX BIOPHARMA AS (NO) 2012-05-03 US disclosed
US-8143211-B2 Bioactive peptides LYTIX BIOPHARMA AS (NO) 2012-03-27 US disclosed
US-8048852-B2 Antimicrobial compounds and formulations LYTIX BIOPHARMA AS (NO) 2011-11-01 US disclosed
EP-1263471-B1 ANTIMICROBIAL COMPOUNDS AND FORMULATIONS LYTIX BIOPHARMA AS (NO) 2011-10-12 EP disclosed
EP-2338522-A1 Antitumoural therapies Lytix Biopharma AS (NO) 2011-06-29 EP disclosed
EP-1109827-B1 BIOACTIVE PEPTIDES LYTIX BIOPHARMA AS (NO) 2011-06-22 EP disclosed
US-20030148936-A1 Bioactive peptides ALPHARMA AS. 2003-08-07 US disclosed
EP-0824962-B1 USE OF AN OXIDATION CATALYST SYSTEM AND PROCESS FOR OXIDATION WITH THE SAME DAICEL CHEM (JP) 2003-05-07 EP disclosed
US-20030022821-A1 Bioactive peptides ALPHARMA AS 2003-01-30 US disclosed
EP-1258292-A1 Oxidation catalytic system and oxidation process using same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-20 EP disclosed
EP-1109831-A2 CYCTOTOXIC PEPTIDES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES ALPHARMA AS (NO) 2001-06-27 EP disclosed
EP-1109827-A2 BIOACTIVE PEPTIDES ALPHARMA AS (NO) 2001-06-27 EP disclosed
WO-2000012542-A2 CYTOTOXIC LACTOFERRIN DERIVATIVES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES ALPHARMA AS (NO) 2000-03-09 WO disclosed
WO-2000012541-A2 CYTOTOXIC PEPTIDES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES ALPHARMA AS (NO) 2000-03-09 WO disclosed
US-5958821-A EPOXIDATION OF AN ALKENE USING A CYCLIC N-HYDROXYIMIDE AND A COCATALYST OF A COMPOUND OF A GROUP 2A OR TRANSITION METAL USING OXYGEN; CATALYST SELECTIVITY; FREE OF PHOSPHO-VANADOMOLYBDIC ACID OR TETRAPHENYLPORPHYRINTOATO MANGANESE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-09-28 US disclosed
EP-0824962-A1 OXIDATION CATALYST SYSTEM AND PROCESS FOR OXIDATION WITH THE SAME DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-02-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108520-A1 Antimicrobial Compounds and Formulations VIP, NONO, CLPTM1 CA1 4497/4885CA2 2554/4885CA4 3733/4885
US-20030148936-A1 Bioactive peptides VIP, NGLY1, HM13 CA1 1870/4885CA2 1355/4885CA4 1540/4885
US-20030022821-A1 Bioactive peptides VIP, LITAF, LNPEP CA1 707/4885CA2 840/4885CA4 835/4885
US-20140037657-A1 INHIBITION OF TUMOR GROWTH STING1, VIP, MIF CA1 1900/4885CA2 873/4885CA4 588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.