Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386122 | 0.89 | CA12 (0.41) | CA12CA9CA2ALDH1A1HPGD | |
| SCHEMBL8386804 | 0.85 | LMNA (0.43) | CA12CA9CA2ALDH1A1HPGD | |
| SCHEMBL827621 | 0.84 | SOAT1 (0.48) | CA12CA9ALDH1A1SOAT1TP53 | |
| SCHEMBL15223811 | 0.82 | KDM5A (0.37) | CA12CA9SOAT1TP53MEN1 | |
| SCHEMBL498627 | 0.82 | CA12 (0.54) | CA12CA9CA2ALDH1A1HPGD | |
| SCHEMBL483128 | 0.82 | CA12 (0.55) | CA12CA9CA2ALDH1A1HPGD | |
| SCHEMBL8382812 | 0.82 | ALDH1A1 (0.52) | CA12CA9CA2ALDH1A1HPGD | |
| SCHEMBL8386642 | 0.82 | CA12 (0.39) | CA12CA9CA2ALDH1A1HPGD | |
| SCHEMBL15223831 | 0.82 | LMNA (0.41) | CA12CA9ALDH1A1CYP1A2CA1 | |
| SCHEMBL11506431 | 0.80 | CA12 (0.46) | CA12CA9CA2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |