Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386709 | 0.89 | LMNA (0.39) | LMNACA12CA1CA9SOAT1 | |
| SCHEMBL8386643 | 0.85 | CA12 (0.40) | LMNACA12CA1CA9SOAT1 | |
| SCHEMBL15223811 | 0.84 | KDM5A (0.37) | LMNACA12CA1CA9SOAT1 | |
| SCHEMBL15223831 | 0.83 | LMNA (0.41) | LMNACA12CA1CA9CYP1A2 | |
| SCHEMBL22113739 | 0.83 | ALDH1A1 (0.46) | LMNACA12CA1CA9MEN1 | |
| SCHEMBL8386797 | 0.81 | LMNA (0.41) | LMNACA12CA1CA9ALDH1A1 | |
| SCHEMBL13717326 | 0.80 | CA12 (0.42) | LMNACA12CA1CA9CYP1A2 | |
| SCHEMBL23169898 | 0.80 | LMNA (0.34) | LMNACA12CA1CA9 | |
| SCHEMBL498027 | 0.79 | CA12 (0.61) | LMNACA12CA1CA9CYP1A2 | |
| SCHEMBL8383135 | 0.79 | LMNA (0.50) | LMNACA12CA1CA9SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3108886-B1 | CONJUGATES OF CC-1065 ANALOGS AND BIFUNCTIONAL LINKERS | SYNTARGA BV (NL) | 2020-06-17 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |