Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.67 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.67 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.67 |
| ▸ | KYNU | Q16719 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 3/20 | 0.60 |
| ▸ | CTSS | P25774 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 3/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199556 | 0.95 | SIRT2 (0.74) | SIRT2SIRT1SIRT3KYNUALDH1A1 | |
| SCHEMBL26222759 | 0.95 | SIRT2 (0.74) | SIRT2SIRT1SIRT3KYNUALDH1A1 | |
| SCHEMBL7362144 | 0.93 | SIRT2 (0.67) | SIRT2SIRT1SIRT3KYNUALDH1A1 | |
| SCHEMBL6477219 | 0.93 | SIRT2 (0.61) | SIRT2SIRT1SIRT3KYNUALDH1A1 | |
| SCHEMBL1840311 | 0.93 | SIRT2 (0.61) | SIRT2SIRT1SIRT3KYNUALDH1A1 | |
| SCHEMBL1161931 | 0.93 | SIRT2 (0.61) | SIRT2SIRT1SIRT3KYNUALDH1A1 | |
| SCHEMBL1840309 | 0.93 | SIRT2 (0.61) | SIRT2SIRT1SIRT3KYNUALDH1A1 | |
| SCHEMBL1111001 | 0.93 | SIRT2 (0.60) | SIRT2SIRT1SIRT3KYNUALDH1A1 | |
| SCHEMBL1110959 | 0.93 | SIRT2 (0.60) | SIRT2SIRT1SIRT3KYNUALDH1A1 | |
| SCHEMBL1110961 | 0.93 | SIRT2 (0.60) | SIRT2SIRT1SIRT3KYNUALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775104-B1 | DIMER DTPA DERIVATIVES AND THEIR METAL COMPLEXES, PHARMACEUTICALS CONTAINING THE SAME, THEIR USE IN DIAGNOSIS AND THERAPY AND PROCESS FOR PREPARING SAID COMPLEXES AND PHARMACEUTICALS | SCHERING AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| US-5695737-A | CONTRAST MEDIA FOR NUCLEAR MAGNETIC RESONANCE | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0775104-A1 | DIMER DTPA DERIVATIVES AND THEIR METAL COMPLEXES, PHARMACEUTICALS CONTAINING THE SAME, THEIR USE IN DIAGNOSIS AND THERAPY AND PROCESS FOR PREPARING SAID COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005167-A1 | DIMER DTPA DERIVATIVES AND THEIR METAL COMPLEXES, PHARMACEUTICALS CONTAINING THE SAME, THEIR USE IN DIAGNOSIS AND THERAPY AND PROCESS FOR PREPARING SAID COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-02-22 | — | — | WO | disclosed |