Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.61 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.57 |
| ▸ | KYNU | Q16719 | 1/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840309 | 1.00 | SIRT2 (0.61) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL6477219 | 1.00 | SIRT2 (0.61) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL3952159 | 0.99 | SIRT2 (0.60) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL3952162 | 0.99 | SIRT2 (0.60) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6528872 | 0.99 | SIRT2 (0.60) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL8447229 | 0.96 | SIRT2 (0.59) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL8447232 | 0.96 | SIRT2 (0.59) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6236103 | 0.95 | SIRT2 (0.58) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6236109 | 0.95 | SIRT2 (0.58) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL8386880 | 0.93 | SIRT2 (0.67) | SIRT2SIRT1SIRT3KYNUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605409-A2 | CYCLIN INHIBITORS | Circle Pharma, Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| US-20250243219-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | CYPRALIS LIMITED (GB) | 2025-07-31 | — | — | US | disclosed |
| US-20250161468-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| EP-4526308-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | Cypralis Limited (GB) | 2025-03-26 | — | — | EP | disclosed |
| US-20240390507-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2024-11-28 | — | — | US | disclosed |
| US-20240218021-A1 | CYCLIN INHIBITORS | CIRCLE PHARMA, INC. | 2024-07-04 | — | — | US | disclosed |
| WO-2024086814-A2 | CYCLIN INHIBITORS | CIRCLE PHARMA, INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| CN-117460743-A | Small molecule VE-PTP inhibitors | 曼宁研究公司 | 2024-01-26 | — | — | CN | disclosed |
| WO-2023223057-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | CYPRALIS LIMITED (GB) | 2023-11-23 | — | — | WO | disclosed |
| US-20230210110-A1 | METHOD FOR INDUCING ENVIRONMENTAL STRESS TOLERANCE IN PLANTS | AJINOMOTO CO., INC. (JP) | 2023-07-06 | — | — | US | disclosed |
| CN-1101908-A | Angiotensin II antagonists | LILLY CO ELI (US) | 1995-04-26 | — | — | CN | disclosed |
| EP-0644887-A1 | PROCESS FOR THE PREPARATION OF CLAVULANIC ACID. | SMITHKLINE BEECHAM PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| EP-0288278-B1 | Chemical derivatives of GHL-CU | PROCYTE CORP (US) | 1994-03-30 | — | — | EP | disclosed |
| WO-1993025557-A1 | PROCESS FOR THE PREPARATION OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1993-12-23 | — | — | WO | disclosed |
| EP-0574174-A2 | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| EP-0293071-B1 | REDOX AMINO ACIDS AND PEPTIDES CONTAINING THEM | UNIVERSITY OF FLORIDA (US) | 1993-09-01 | — | — | EP | disclosed |
| EP-0293071-A1 | Redox amino acids and peptides containing them | UNIVERSITY OF FLORIDA (US) | 1988-11-30 | — | — | EP | disclosed |
| EP-0288278-A2 | Chemical derivatives of GHL-CU | PROCYTE CORPORATION (US) | 1988-10-26 | — | — | EP | disclosed |
| EP-0190736-A2 | Chemical derivatives of GHL-Cu | PROCYTE CORPORATION (US) | 1986-08-13 | — | — | EP | disclosed |
| EP-0175180-A1 | Histargin-related compounds, a process for their preparation and their use as medicaments | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1986-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210110-A1 | METHOD FOR INDUCING ENVIRONMENTAL STRESS TOLERANCE IN PLANTS | DAO, ALAD, BCAT1 | SIRT2 3556/4885SIRT1 2971/4885SIRT3 4204/4885 |
| US-20240218021-A1 | CYCLIN INHIBITORS | CCNI, CCNC, CDK2 | SIRT2 2480/4885SIRT1 1851/4885SIRT3 2971/4885 |
| US-20250161468-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRL1 | SIRT2 4193/4885SIRT1 2554/4885SIRT3 3275/4885 |
| US-20240390507-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRL1 | SIRT2 4193/4885SIRT1 2554/4885SIRT3 3275/4885 |
| US-20250243219-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | CASP3, TNNC1, BAD | SIRT2 1103/4885SIRT1 453/4885SIRT3 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.