Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.61 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.57 |
| ▸ | KYNU | Q16719 | 1/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840311 | 1.00 | SIRT2 (0.61) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL6477219 | 1.00 | SIRT2 (0.61) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL3952159 | 0.99 | SIRT2 (0.60) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL3952162 | 0.99 | SIRT2 (0.60) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6528872 | 0.99 | SIRT2 (0.60) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL8447229 | 0.96 | SIRT2 (0.59) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL8447232 | 0.96 | SIRT2 (0.59) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6236103 | 0.95 | SIRT2 (0.58) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6236109 | 0.95 | SIRT2 (0.58) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL8386880 | 0.93 | SIRT2 (0.67) | SIRT2SIRT1SIRT3KYNUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460743-A | Small molecule VE-PTP inhibitors | 曼宁研究公司 | 2024-01-26 | — | — | CN | disclosed |
| EP-2769738-B1 | Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists | INVIVOGEN (FR) | 2016-07-20 | — | — | EP | disclosed |
| US-9295732-B2 | Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists | INVIVOGEN (FR) | 2016-03-29 | — | — | US | disclosed |
| US-8957205-B2 | Cycloalkane carboxamide derivatives and production process of same | SEIKAGAKU CORPORATION (JP) | 2015-02-17 | — | — | US | disclosed |
| US-8829209-B2 | Cycloalkylcarbonylamino acid ester derivative and process for producing the same | SEIKAGAKU CORPORATION (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20140242108-A1 | Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists | CAYLA (FR) | 2014-08-28 | — | — | US | disclosed |
| EP-2769738-A1 | Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists | Invivogen (FR) | 2014-08-27 | — | — | EP | disclosed |
| US-20110257028-A1 | Method for selectively binding a substrate to sorbents by way of at least bivalent bonds | INSTRACTION GMBH (DE) | 2011-10-20 | — | — | US | disclosed |
| US-20110257028-A1 | Method for selectively binding a substrate to sorbents by way of at least bivalent bonds | INSTRACTION GMBH (DE) | 2011-10-20 | — | — | US | disclosed |
| EP-2036920-B1 | CYCLOALKYLCARBONYLAMINO ACID ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SEIKAGAKU KOGYO CO LTD (JP) | 2011-05-18 | — | — | EP | disclosed |
| US-20090137799-A1 | Cycloalkylcarbonylamino Acid Ester Derivative and Process for Producing The Same | SEIKAGAKU CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-2036920-A1 | CYCLOALKYLCARBONYLAMINO ACID ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SEIKAGAKU CORPORATION (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1972615-A1 | CYCLOALKANECARBOXAMIDE DERIVATIVE AND METHOD FOR PRODUCING SAME | SEIKAGAKU CORPORATION (JP) | 2008-09-24 | — | — | EP | disclosed |
| EP-0751952-B1 | DISPLACEMENT CHROMATOGRAPHY OF PROTEINS USING LOW MOLECULAR WEIGHT DISPLACERS | CRAMER STEVEN M (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-0751952-A4 | DISPLACEMENT CHROMATOGRAPHY OF PROTEINS USING LOW MOLECULAR WEIGHT DISPLACERS | CRAMER STEVEN M (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5606033-A | PURIFYING PROTEIN BY LOADING ONTO ION EXCHANGE STATIONARY PHASE AND DISPLACING USING LOW MOLECULAR WEIGHT ANIONIC DISPLACER | CRAMER STEVEN M (US) | 1997-02-25 | — | — | US | disclosed |
| EP-0751952-A1 | DISPLACEMENT CHROMATOGRAPHY OF PROTEINS USING LOW MOLECULAR WEIGHT DISPLACERS | Cramer, Steven M. (US) | 1997-01-08 | — | — | EP | disclosed |
| US-5478924-A | Purification by ion exchanging with cationic exchanger | CRAMER STEVEN M (US) | 1995-12-26 | — | — | US | disclosed |
| WO-1995022555-A1 | DISPLACEMENT CHROMATOGRAPHY OF PROTEINS USING LOW MOLECULAR WEIGHT DISPLACERS | CRAMER STEVEN M (US) | 1995-08-24 | — | — | WO | disclosed |
| EP-0050800-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257028-A1 | Method for selectively binding a substrate to sorbents by way of at least bivalent bonds | SPR, ABCG2, SHBG | SIRT2 1820/4885SIRT1 1776/4885SIRT3 1369/4885 |
| US-20140242108-A1 | Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists | TLR7, TLR8, TLR9 | SIRT2 400/4885SIRT1 365/4885SIRT3 699/4885 |
| US-20090137799-A1 | Cycloalkylcarbonylamino Acid Ester Derivative and Process for Producing The Same | CTSK, CTSS, CTSE | SIRT2 3172/4885SIRT1 3106/4885SIRT3 2154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.