Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22777216 | 0.82 | CYP1A2 (0.64) | CYP1A2CYP2C9HIF1AMAPTESR1 | |
| SCHEMBL28947786 | 0.82 | CYP1A2 (0.64) | CYP1A2CYP2C9HIF1AMAPTESR1 | |
| Metaxon SCHEMBL8386962 | 0.81 | TDP1 (0.59) | CYP1A2CYP2C9HIF1AMAPTESR1 | |
| SCHEMBL27351928 | 0.80 | CYP1A2 (0.69) | CYP1A2CYP2C9HIF1AMAPTESR1 | |
| SCHEMBL4887579 | 0.80 | CYP1A2 (0.69) | CYP1A2CYP2C9HIF1AMAPTESR1 | |
| SCHEMBL8553263 | 0.79 | TDP1 (0.47) | CYP1A2CYP2C9HIF1AMAPTESR1 | |
| SCHEMBL11632929 | 0.79 | VDR (0.67) | CYP1A2CYP2C9HIF1AMAPTESR1 | |
| SCHEMBL5416139 | 0.79 | CYP1A2 (0.68) | CYP1A2CYP2C9HIF1AMAPTESR1 | |
| SCHEMBL11654381 | 0.78 | MEN1 (0.69) | CYP1A2CYP2C9HIF1AMAPTESR1 | |
| SCHEMBL9530366 | 0.78 | TSHR (0.50) | CYP1A2CYP2C9HIF1AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |