Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386963 | 0.79 | CYP1A2 (0.60) | TDP1ESR1POLBESR2CTDSP1 | |
| SCHEMBL16794414 | 0.73 | TDP1 (0.55) | TDP1MAPTALDH1A1L3MBTL1MAPK1 | |
| Metaxon SCHEMBL8553259 | 0.72 | TDP1 (0.69) | TDP1ESR1POLBESR2CTDSP1 | |
| SCHEMBL7876706 | 0.72 | TDP1 (0.56) | TDP1ESR1POLBESR2CTDSP1 | |
| SCHEMBL4658772 | 0.72 | TDP1 (0.58) | TDP1ESR1POLBESR2CTDSP1 | |
| SCHEMBL158457 | 0.71 | MAPT (0.67) | TDP1ESR1POLBESR2CTDSP1 | |
| SCHEMBL29860787 | 0.71 | MAPT (0.67) | TDP1ESR1POLBESR2CTDSP1 | |
| SCHEMBL4887815 | 0.70 | ESR1 (0.72) | TDP1ESR1POLBESR2CTDSP1 | |
| Ammonia Solution, Strong SCHEMBL29010268 | 0.70 | MAPT (0.65) | TDP1ESR1POLBESR2CTDSP1 | |
| SCHEMBL1694924 | 0.70 | TDP1 (0.74) | TDP1MAPTALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846105-A1 | HERBICIDAL SUBSTITUTED 3-ARYL-PYRAZOLES | MONSANTO COMPANY (US) | 1998-06-10 | — | — | EP | disclosed |