SCHEMBL8387155

SCHEMBL8387155

CCCCCCC1(C(=O)OC(C)(C)C)OO1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
SPHK1 Q9NYA1 1/20 0.34
CES1 P23141 7/20 0.32
CES2 O00748 5/20 0.32
FAAH O00519 6/20 0.32
NAAA Q02083 1/20 0.32
DGKA P23743 1/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3681042 0.77 CA1 (0.32)
SCHEMBL1555946 0.74 CYP4F2 (0.52) CYP4F2CYP4A11SPHK1CES1CES2
SCHEMBL8873142 0.74 GPR84 (0.43) CES1CES2MEN1KMT2AHSD17B10
SCHEMBL3296089 0.73 SPHK1 (0.33) SPHK1CES1CES2
SCHEMBL9566594 0.73 SPHK1 (0.32) CYP4F2CYP4A11SPHK1
SCHEMBL11618913 0.72 CTSK (0.32) MEN1KMT2A
SCHEMBL2221257 0.72 MEN1 (0.38) CES1CES2FAAHMEN1CYP1A2
SCHEMBL2219784 0.72 MEN1 (0.38) CES1CES2FAAHMEN1CYP1A2
SCHEMBL18905948 0.70 CYP4F2 (0.40) CYP4F2CYP4A11SPHK1
Heptane SCHEMBL29285178 0.69 GPR84 (0.46) CES1CES2MEN1CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640633-B1 Process for the preparation of low viscosity polymer polyols with improved dispersion stability ARCO CHEM TECH (US) 1999-04-21 EP disclosed
US-5496894-A POLYURETHANES AND UNSATURATED MONOMERS FOR POLYMERS ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1996-03-05 US disclosed
EP-0640633-A1 Low viscosity polymer polyols with improved dispersion stability ARCO Chemical Technology, L.P. (US) 1995-03-01 EP disclosed
US-5364906-A Starting materials for high load-bearing polyurethane foams ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-11-15 US disclosed
US-5358984-A Storage stable dispersions of addition polymer particles in polyoxyalkylene ethers with homo- or copolymers of acrylic anhydrides and/or partially esterified acrylic anhydrides as dispersants ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-10-25 US disclosed
EP-0353070-B1 Polyol polyacrylate dispersants ARCO CHEM TECH (US) 1994-03-16 EP disclosed
US-5225481-A Storage stability of polymer polyols with ester interchange ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-07-06 US disclosed
EP-0537028-A1 Polymer polyol dispersants from polymers containing anhydride groups ARCO CHEMICAL TECHNOLOGY, INC. (US) 1993-04-14 EP disclosed
US-5021506-A Stable, low viscosity ARCO CHEMICAL TECHNOLOGY, INC. (US) 1991-06-04 US disclosed
EP-0353070-A2 Polyol polyacrylate dispersants ARCO Chemical Technology, L.P. (US) 1990-01-31 EP disclosed