SCHEMBL3296089

SCHEMBL3296089

CCCCCCCCCCCCCCCCCC1(OC(=O)OC(C)(C)C)OO1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
EPHX1 P07099 1/20 0.33
POLA1 P09884 2/20 0.32
DNTT P04053 1/20 0.31
POLB P06746 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
CES2 O00748 4/20 0.31
CES1 P23141 3/20 0.31
ZDHHC7 Q9NXF8 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9842536 0.88 EPHX1 (0.31) EPHX1POLA1DNTTPOLB
SCHEMBL8973464 0.79 HDAC6 (0.32) HDAC1HDAC2HDAC6
SCHEMBL11228349 0.79 NAAA (0.42) EPHX1POLB
SCHEMBL11603667 0.79 NAAA (0.34) EPHX1POLA1CES2
SCHEMBL9752548 0.78 ALDH1A1 (0.36) HDAC1HDAC2HDAC6
SCHEMBL27464481 0.78 GPR84 (0.39) EPHX1
SCHEMBL12233857 0.75 DGKA (0.48) POLA1POLBCES2CES1MAPT
SCHEMBL9752489 0.74 HDAC6 (0.32) HDAC6
SCHEMBL8387155 0.73 CYP4F2 (0.36) SPHK1CES2CES1
SCHEMBL18663443 0.73 DGKA (0.33) POLA1DNTTPOLBCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723421-B2 Molding compositions with solid thermoplastic elastomer thickeners and products obtained therefrom Guzauskas, Robert (US) 2010-05-25 US disclosed
US-20070249774-A1 Molding compositions with solid thermoplastic elastomer thickeners and products obtained therefrom GUZAUSKAS ROBERT 2007-10-25 US disclosed
US-7183334-B2 Low temperature molding compositions with solid thermoplastic elastomer thickeners and fiber reinforcement REINFORCED POLYMERS, INC. (US) 2007-02-27 US disclosed
US-7132469-B2 Molding compositions with solid thermoplastic elastomer thickeners and products obtained therefrom REINFORCED POLYMERS, INC. (US) 2006-11-07 US disclosed
US-20040063845-A1 Molding compositions with solid thermoplastic elastomer thickeners and products obtained therefrom REINFORCED POLYMERS, INC. (US) 2004-04-01 US disclosed
US-20030134925-A1 Low temperature molding compositions with solid thermoplastic elastomer thickeners and fiber reinforcement REINFORCED POLYMERS, INC. 2003-07-17 US disclosed
US-6433037-B1 ACRYLIC RESIN ABSORBS FREE-RADICAL POLYMERIZABLE UNSATURATED MONOMER, OLIGOMER, OR POLYMER AND MATURES INTO MOLDABLE DOUGH; DENTISTRY, AUTOMOBILES, BATHROOM FIXTURES; LOW TEMPERATURE AND PRESSURE REINFORCED POLYMERS, INC. 2002-08-13 US disclosed
US-6103779-A MIXING SOLID ACRYLIC RESIN WITH ONE OR MORE LIQUID UNSATURATED MONOMERS, OLIGOMERS OR POLYMERS AND INSOLUBLE LONG FIBER REINFORCEMENT, AGING MIXTURE TO ALLOW SOLID RESIN TO ABSORB LIQUID REINFORCED POLMERS, INC. (US) 2000-08-15 US disclosed
US-5430116-A Polymers and oligomers of bile acid derivatives, process for their preparation and their use as pharmaceuticals HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-04 US disclosed
US-5051465-A Organopolysiloxane, silica and an organic peroxide which is hot air vulcanizable for moldings SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-09-24 US disclosed