Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 2/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17078164 | 0.90 | CA2 (0.59) | CA2ANPEPRNPEPDNPEPALPI | |
| SCHEMBL5556436 | 0.90 | CA2 (0.59) | CA2ANPEPRNPEPDNPEPALPI | |
| SCHEMBL13340021 | 0.85 | CA2 (0.64) | CA2SMN1; SMN2HTTANPEPRNPEP | |
| SCHEMBL17337726 | 0.84 | CA2 (0.66) | CA2SMN1; SMN2HTTANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL18787086 | 0.83 | CA2 (0.65) | CA2SMN1; SMN2HTTANPEPRNPEP | |
| SCHEMBL4831966 | 0.82 | CA2 (0.52) | CA2 | |
| SCHEMBL6443119 | 0.82 | CA2 (0.64) | CA2SMN1; SMN2HTTANPEPRNPEP | |
| SCHEMBL7066414 | 0.82 | CTSD (0.44) | CA2SMN1; SMN2HTT | |
| SCHEMBL23742786 | 0.80 | CA2 (0.50) | CA2CTSC | |
| SCHEMBL21010316 | 0.79 | SLC15A1 (0.64) | CA2ANPEPRNPEPDNPEPALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793641-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-04-21 | — | — | EP | disclosed |
| US-5866717-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-02-02 | — | — | US | disclosed |
| EP-0793641-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016931-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-06-06 | — | — | WO | disclosed |