Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PER2 | O15055 | 1/20 | 0.38 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314947 | 0.98 | TP53 (0.49) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL10797166 | 0.84 | TAAR1 (0.45) | MAPTALDH1A1HTTTDP1LMNA | |
| SCHEMBL7959682 | 0.83 | MAPT (0.46) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL186732 | 0.82 | TP53 (0.48) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL10663663 | 0.82 | RAB9A (0.50) | TP53MAPTALDH1A1HTTPOLB | |
| SCHEMBL6845542 | 0.81 | TP53 (0.47) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9762186 | 0.81 | TP53 (0.46) | TP53MAPTALDH1A1HSD17B10GLA | |
| SCHEMBL9081406 | 0.80 | TP53 (0.46) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL11350458 | 0.80 | TP53 (0.46) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL10660448 | 0.80 | RAB9A (0.42) | TP53MAPTALDH1A1HTTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916759-A | AMINO ACID SEQUENCE WITHOUT SPECIES SIGNAL SEQUENCE INCREASES YIELD IN GENETICALLY ENGINEERED EXPRESSION SYSTEMS; FOR DETERMINATION OF CHOLESTEROL IN SAMPLES | BOEHRINGER MANNHEIM GMBH (DE) | 1999-06-29 | — | — | US | disclosed |