SCHEMBL10797166

SCHEMBL10797166

CCN(c1cccc(Cl)c1)C(C)S(=O)(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.45
S1PR1 P21453 1/20 0.43
RORC P51449 5/20 0.41
MAPT P10636 4/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PER2 O15055 1/20 0.40
CRY1 Q16526 1/20 0.40
CRY2 Q49AN0 1/20 0.40
HTR3E A5X5Y0 1/20 0.40
HTR3B O95264 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40
HTR3C Q8WXA8 1/20 0.40
NPC1 O15118 1/20 0.39
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9314947 0.85 TP53 (0.49) MAPTALDH1A1LMNAHTTTDP1
SCHEMBL8388252 0.84 TP53 (0.48) MAPTALDH1A1LMNAHTTTDP1
SCHEMBL9762186 0.82 TP53 (0.46) TAAR1MAPTALDH1A1LMNAMEN1
SCHEMBL11689252 0.79 TAAR1 (0.47) TAAR1S1PR1RORCMAPTALDH1A1
SCHEMBL11793320 0.79 S1PR1 (0.48) TAAR1S1PR1RORCMAPTALDH1A1
SCHEMBL10799265 0.77 PER2 (0.41) TAAR1RORCMAPTLMNAPER2
SCHEMBL11691829 0.74 S1PR1 (0.55) TAAR1S1PR1MAPTALDH1A1
SCHEMBL354691 0.74 TAAR1 (0.52) TAAR1RORCMAPTALDH1A1LMNA
SCHEMBL10794729 0.74 HTT (0.40) RORCMAPTLMNAHTTPER2
SCHEMBL6699042 0.74 S100B (0.51) S1PR1MAPTALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4652634-A Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-24 US disclosed
US-4430259-A Water-soluble disazo compounds suitable as fiber-reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1984-02-07 US disclosed