Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PER2 | O15055 | 1/20 | 0.38 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388252 | 0.98 | TP53 (0.48) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL10797166 | 0.85 | TAAR1 (0.45) | MAPTALDH1A1HTTTDP1LMNA | |
| SCHEMBL7959682 | 0.84 | MAPT (0.46) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL186732 | 0.84 | TP53 (0.48) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL10663663 | 0.83 | RAB9A (0.50) | TP53MAPTALDH1A1HTTPOLB | |
| SCHEMBL6845542 | 0.82 | TP53 (0.47) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9762186 | 0.82 | TP53 (0.46) | TP53MAPTALDH1A1HSD17B10GLA | |
| SCHEMBL9081406 | 0.81 | TP53 (0.46) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL11350458 | 0.81 | TP53 (0.46) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL10660448 | 0.81 | RAB9A (0.42) | TP53MAPTALDH1A1HTTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187138-B1 | MICROORGANISM AND PLASMID FOR THE CONSTITUTIVE SYNTHESIS OF CREATINE AMIDINO HYDROLASE AND METHOD FOR THEIR PRODUCTION | Roche Diagnostics GmbH (DE) | 1992-04-15 | — | — | EP | claimed |
| US-5094943-A | Superoxide dimutase | BOEHRINGER MANNHEIM GMBH (DE) | 1992-03-10 | — | — | US | claimed |
| US-4861717-A | Microorganisms and plasmids for the constitutive formation of creatinamidinohydrolase and processes for the production thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1989-08-29 | — | — | US | claimed |
| EP-0186134-B1 | MEANS FOR IMPROVING THE DETERMINATION OF OXIDASE REACTIONS PRODUCING HYDROGEN PEROXYDE, AND THEIR USE | Roche Diagnostics GmbH (DE) | 1989-02-15 | — | — | EP | claimed |
| EP-0186134-A1 | Means for improving the determination of oxidase reactions producing hydrogen peroxyde, and their use | Roche Diagnostics GmbH (DE) | 1986-07-02 | — | — | EP | claimed |
| CN-216978839-U | Tear sugar detection device | 上海微银生物技术有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-113791067-A | Tear sugar detection device and production process thereof | 上海微银生物技术有限公司 | 2021-12-14 | — | — | CN | disclosed |
| US-5315035-A | Hydrogen peroxide detection | BOEHRINGER MANNHEIM GMBH (DE) | 1994-05-24 | — | — | US | disclosed |
| US-5196314-A | Colorimetric, tetrazole compunds to reduce interference | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0187138-B1 | MICROORGANISM AND PLASMID FOR THE CONSTITUTIVE SYNTHESIS OF CREATINE AMIDINO HYDROLASE AND METHOD FOR THEIR PRODUCTION | Roche Diagnostics GmbH (DE) | 1992-04-15 | — | — | EP | disclosed |
| EP-0239931-B1 | PROCESS AND REAGENT FOR THE DETERMINATION OF SUBSTRATES OR ENZYME ACTIVITIES | Roche Diagnostics GmbH (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-5094943-A | Superoxide dimutase | BOEHRINGER MANNHEIM GMBH (DE) | 1992-03-10 | — | — | US | disclosed |
| US-4861717-A | Microorganisms and plasmids for the constitutive formation of creatinamidinohydrolase and processes for the production thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1989-08-29 | — | — | US | disclosed |
| US-4851335-A | HIGH DENSITY LIPOPROTEIN | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0239931-A2 | Process and reagent for the determination of substrates or enzyme activities | Roche Diagnostics GmbH (DE) | 1987-10-07 | — | — | EP | disclosed |
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| EP-0187138-A2 | Microorganism and plasmid for the constitutive synthesis of creatine amidino hydrolase and method for their production | Roche Diagnostics GmbH (DE) | 1986-07-09 | — | — | EP | disclosed |
| EP-0175250-A2 | Agent and process for the determination of redox systems | Roche Diagnostics GmbH (DE) | 1986-03-26 | — | — | EP | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| EP-0051808-A2 | Water-soluble monoazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-19 | — | — | EP | disclosed |