Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.55 |
| ▸ | DRD4 | P21917 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388326 | 0.83 | DRD2 (0.51) | DRD2DRD4DRD3LTA4HALDH1A1 | |
| SCHEMBL1445771 | 0.83 | DRD2 (0.75) | DRD2DRD4DRD3ALDH1A1MAPK1 | |
| SCHEMBL8616998 | 0.82 | KCNA3 (0.67) | DRD2DRD4DRD3LTA4HALDH1A1 | |
| Diphenylsulfane SCHEMBL1047048 | 0.81 | LTA4H (0.53) | LTA4H | |
| SCHEMBL8391278 | 0.80 | KCNA3 (0.56) | DRD2DRD4DRD3LTA4HALDH1A1 | |
| SCHEMBL9808097 | 0.78 | KCNA3 (0.67) | DRD2DRD4DRD3LTA4HALDH1A1 | |
| SCHEMBL8546938 | 0.78 | KCNA3 (0.50) | KCNA3NPC1RAB9A | |
| SCHEMBL8391270 | 0.77 | FFAR1 (0.63) | DRD2DRD4DRD3LTA4HNPC1 | |
| SCHEMBL3094303 | 0.76 | FFAR1 (0.64) | DRD2DRD4DRD3LTA4HKCNA3 | |
| SCHEMBL17478146 | 0.76 | HRH3 (0.42) | LTA4HALDH1A1KCNA3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965743-A | AS ANTIHYPERLIPEMIC AGENT; THERAPEUTIC AND PREVENTIVE DRUGS FOR ARTERIOSCLEROSIS | NIPPON SODA CO., LTD. (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0757988-A1 | IMIDAZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | NIPPON SODA CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |