Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 11/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388869 | 0.90 | MEN1 (0.44) | PLA2G2AMEN1KMT2APLA2G1BMCL1 | |
| SCHEMBL8387525 | 0.88 | PLA2G2A (0.49) | PLA2G2AMEN1KMT2APLA2G1BMAPK1 | |
| SCHEMBL9057381 | 0.83 | ELANE (0.44) | PLA2G2AMEN1KMT2APLA2G1BMCL1 | |
| SCHEMBL8388486 | 0.82 | MEN1 (0.48) | PLA2G2AMEN1KMT2APLA2G1BMAPK1 | |
| SCHEMBL27549304 | 0.81 | MAPT (0.44) | PLA2G2AMEN1KMT2APLA2G1BMCL1 | |
| SCHEMBL8388247 | 0.80 | MEN1 (0.42) | PLA2G2AMEN1KMT2APLA2G1BMAPK1 | |
| SCHEMBL8387036 | 0.79 | MEN1 (0.48) | PLA2G2AMEN1KMT2APLA2G1BMCL1 | |
| SCHEMBL8390508 | 0.79 | THRB (0.46) | PLA2G2AMEN1KMT2APLA2G1BMAPK1 | |
| SCHEMBL8388364 | 0.78 | PTGDR2 (0.51) | PLA2G2AMEN1KMT2APLA2G1BMAPK1 | |
| SCHEMBL8388323 | 0.78 | MEN1 (0.44) | PLA2G2AMEN1KMT2APLA2G1BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877199-A | ALZHEIMER'S DISEASE; SEDATIVE | SANKYO COMPANY, LIMITED (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |