Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27471973 | 0.89 | MAPT (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8390508 | 0.85 | THRB (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8387036 | 0.85 | MEN1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8387525 | 0.85 | PLA2G2A (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8388364 | 0.84 | PTGDR2 (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8388323 | 0.84 | MEN1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8388869 | 0.84 | MEN1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8388054 | 0.83 | MEN1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8388247 | 0.82 | MEN1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8388463 | 0.82 | PLA2G2A (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877199-A | ALZHEIMER'S DISEASE; SEDATIVE | SANKYO COMPANY, LIMITED (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |