Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.66 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.66 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.66 |
| ▸ | SRM | P19623 | 4/20 | 0.64 |
| ▸ | SMS | P52788 | 2/20 | 0.64 |
| ▸ | PRKACA | P17612 | 2/20 | 0.63 |
| ▸ | PNMT | P11086 | 1/20 | 0.62 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.62 |
| ▸ | NADK | O95544 | 1/20 | 0.62 |
| ▸ | AHCY | P23526 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.61 |
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.61 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.61 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610250 | 0.92 | EHMT1 (0.71) | PRKACANADK | |
| SCHEMBL1900946 | 0.90 | EHMT1 (0.70) | DOT1LPRKACANADKAHCYADORA1 | |
| SCHEMBL12450414 | 0.86 | P2RY1 (0.72) | ADORA1SMN1; SMN2DNPH1PRKAB2TRPM2 | |
| SCHEMBL10886673 | 0.85 | DOT1L (0.66) | DOT1LDNMT3BPRMT7SRMSMS | |
| SCHEMBL6569310 | 0.85 | ADORA1 (0.73) | DOT1LNADKAHCYADORA1SMN1; SMN2 | |
| SCHEMBL8007640 | 0.85 | DOT1L (0.65) | DOT1LDNMT3BPRMT7SRMSMS | |
| SCHEMBL9549055 | 0.84 | RNASEL (0.62) | SMN1; SMN2SRCP2RY2P2RY1 | |
| SCHEMBL6026064 | 0.84 | PRKACA (0.67) | PRKACAADORA1SMN1; SMN2DNPH1PRKAB2 | |
| SCHEMBL939593 | 0.84 | ADORA1 (0.71) | DOT1LNADKAHCYADORA1SMN1; SMN2 | |
| SCHEMBL8708990 | 0.84 | ADORA1 (0.71) | DOT1LNADKAHCYADORA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928862-A | CONTACTING SAMPLE WITH LABELED POLYNUCLEOTIDE PROBES CAPABLE OF TWO POSTIONS, EITHER BOUND TO EACH OTHER WHERE LABELS CAN INTERACT OR ONE BOUND TO TARGET IN SAMPLE; MONITORING FOR SIGNAL INDICATIVE OF PRESENCE OF TARGET | AMOCO CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0232967-B1 | COMPETITIVE HOMOGENEOUS ASSAY | AMOCO CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0232967-A2 | Competitive homogeneous Assay | AMOCO CORPORATION (US) | 1987-08-19 | — | — | EP | disclosed |