Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 7/20 | 0.67 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.58 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.58 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.58 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886673 | 0.85 | DOT1L (0.66) | DNPH1PRKAB2TRPM2LDHAADRB2 | |
| SCHEMBL8388991 | 0.84 | DOT1L (0.66) | PRKACADNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL6026018 | 0.83 | P2RY1 (0.70) | DNPH1PRKAB2TRPM2LDHAADRB2 | |
| SCHEMBL6828798 | 0.81 | ADORA1 (0.70) | DNPH1PRKAB2TRPM2LDHAADRB2 | |
| SCHEMBL7642296 | 0.80 | PRKACA (0.65) | PRKACADNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL8007640 | 0.80 | DOT1L (0.65) | DNPH1PRKAB2TRPM2LDHAADRB2 | |
| SCHEMBL12450414 | 0.80 | P2RY1 (0.72) | DNPH1PRKAB2TRPM2LDHAADRB2 | |
| SCHEMBL8982622 | 0.80 | ADORA3 (0.67) | PRKACADNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL8328542 | 0.79 | ADORA1 (0.74) | DNPH1PRKAB2TRPM2LDHAADRB2 | |
| SCHEMBL2793634 | 0.79 | ADORA1 (0.67) | DNPH1PRKAB2TRPM2LDHAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4108774-A1 | ARTIFICIAL NUCLEIC ACID MOLECULES | CureVac AG (DE) | 2022-12-28 | — | — | EP | disclosed |
| EP-3341482-B1 | ARTIFICIAL NUCLEIC ACID MOLECULES | CUREVAC AG (DE) | 2022-07-06 | — | — | EP | disclosed |
| US-20180237786-A1 | ARTIFICIAL NUCLEIC ACID MOLECULES | CUREVAC AG (DE) | 2018-08-23 | — | — | US | disclosed |
| EP-3341482-A1 | ARTIFICIAL NUCLEIC ACID MOLECULES | CureVac AG (DE) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017036580-A1 | ARTIFICIAL NUCLEIC ACID MOLECULES | CUREVAC AG (DE) | 2017-03-09 | — | — | WO | disclosed |
| EP-1446505-A4 | PRE-EXISTING NUCLEIC ACIDS COVALENTLY ATTACHED TO A METAL SURFACE OR A METAL CLUSTER, INTERMEDIATES THEREOF AND METHODS OF USING SAME | YEDA RES & DEV (IL) | 2006-03-08 | — | — | EP | disclosed |
| US-20040248134-A1 | Pre-existing nucleic acids covalently attached to a metal surface of a metal cluster, intermediates thereof and methods of using same | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2004-12-09 | — | — | US | disclosed |
| EP-1446505-A2 | PRE-EXISTING NUCLEIC ACIDS COVALENTLY ATTACHED TO A METAL SURFACE OR A METAL CLUSTER, INTERMEDIATES THEREOF AND METHODS OF USING SAME | YEDA RESEARCH AND DEVELOPMENT CO., Ltd. (IL) | 2004-08-18 | — | — | EP | disclosed |
| US-6605713-B1 | Contacting D-nucleic acids with a racemic mixture of the target molecule and allow for binding; producing L-nucleic acids; in vitro selection of DNA/RNA with high binding affinity and stability | FURSTE JENS PETER (DE) | 2003-08-12 | — | — | US | disclosed |
| WO-2003038108-A2 | PRE-EXISTING NUCLEIC ACIDS COVALENTLY ATTACHED TO A METAL SURFACE OR A METAL CLUSTER, INTERMEDIATES THEREOF AND METHODS OF USING SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-05-08 | — | — | WO | disclosed |
| EP-0934331-B1 | MIRROR-SYMMETRICAL SELECTION AND EVOLUTION OF NUCLEIC ACIDS | FUERSTE JENS PETER (DE) | 2002-11-27 | — | — | EP | disclosed |