Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388424 | 0.79 | MGLL (0.42) | MGLLCYP2C9CYP2C19MAPK14POLB | |
| SCHEMBL8489221 | 0.63 | SLC9A1 (0.40) | MGLLLMNACYP3A4 | |
| SCHEMBL19766699 | 0.63 | HTT (0.90) | MGLLCYP2C9CYP2C19MAPK14POLB | |
| SCHEMBL11714770 | 0.63 | HTT (0.90) | MGLLCYP2C9CYP2C19MAPK14POLB | |
| SCHEMBL12766946 | 0.62 | HTT (0.72) | CYP2C9CYP2C19POLBHTTKDM4E | |
| SCHEMBL17502718 | 0.62 | HTT (0.62) | MGLLCYP2C9CYP2C19MAPK14POLB | |
| SCHEMBL17502708 | 0.61 | HTT (0.57) | MGLLCYP2C9CYP2C19MAPK14POLB | |
| SCHEMBL2540114 | 0.60 | HTT (0.90) | CYP2C9CYP2C19MAPK14POLBHTT | |
| SCHEMBL16015253 | 0.60 | HTT (0.63) | CYP2C9CYP2C19MAPK14POLBHTT | |
| SCHEMBL17502656 | 0.60 | HTT (0.62) | MGLLCYP2C9CYP2C19MAPK14POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856274-A | 4-benzoyl isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |