Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.34 |
| ▸ | ELOVL6 | Q9H5J4 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494381 | 0.76 | LMNA (0.37) | SLC9A1CACNA1BLMNAEEDMGLL | |
| SCHEMBL8489111 | 0.74 | CACNA1B (0.38) | SLC9A1CACNA1BLMNAEEDHCRTR1 | |
| SCHEMBL8389458 | 0.73 | MGLL (0.41) | MGLL | |
| SCHEMBL8606607 | 0.71 | LMNA (0.43) | SLC9A1CACNA1BLMNAEEDMGLL | |
| SCHEMBL8388424 | 0.67 | MGLL (0.42) | LMNAHCRTR2MGLL | |
| SCHEMBL8391795 | 0.67 | CYP2C9 (0.39) | SLC9A1MGLL | |
| SCHEMBL8606545 | 0.66 | LMNA (0.40) | SLC9A1CACNA1BLMNAEEDMGLL | |
| SCHEMBL8390891 | 0.66 | MGLL (0.43) | MGLL | |
| SCHEMBL8607785 | 0.65 | LMNA (0.37) | SLC9A1CACNA1BLMNAEEDHRH1 | |
| SCHEMBL8491925 | 0.65 | LMNA (0.36) | SLC9A1LMNAEEDHCRTR2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |