Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392107 | 0.83 | CYP3A4 (0.46) | HSD17B10ALOX15ALDH1A1HPGDALOX12 | |
| SCHEMBL11317922 | 0.83 | HSD17B10 (0.50) | HSD17B10ALOX15ALDH1A1HPGDALOX12 | |
| SCHEMBL768507 | 0.83 | ALDH1A1 (0.61) | HSD17B10ALOX15ALDH1A1HPGDALOX12 | |
| SCHEMBL28310444 | 0.81 | NR1H4 (0.43) | HSD17B10ALOX15ALDH1A1HPGDALOX12 | |
| SCHEMBL818330 | 0.81 | HSD17B10 (0.48) | HSD17B10ALOX15ALDH1A1HPGDALOX12 | |
| SCHEMBL16579383 | 0.78 | TSHR (0.44) | HSD17B10ALOX15ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL30017641 | 0.78 | TSHR (0.44) | HSD17B10ALOX15ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8389819 | 0.78 | HSD17B10 (0.44) | HSD17B10ALOX15ALDH1A1HPGDALOX12 | |
| SCHEMBL16579355 | 0.77 | CYP3A4 (0.50) | ALOX15ALDH1A1SMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL3338261 | 0.77 | PDE10A (0.50) | HSD17B10ALOX15ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750607-B1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |