SCHEMBL768507

SCHEMBL768507

CC(C)(C)c1cc(Cl)ccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.61
▸ ALOX15 P16050 5/20 0.61
▸ HSD17B10 Q99714 5/20 0.61
▸ HTT P42858 3/20 0.61
▸ LMNA P02545 2/20 0.61
▸ CYP2C9 P11712 2/20 0.61
▸ NR1I2 O75469 1/20 0.61
▸ MIF P14174 1/20 0.61
▸ TYR P14679 1/20 0.61
▸ NFE2L2 Q16236 1/20 0.61
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ MAPT P10636 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ CYP1A2 P05177 1/20 0.54
▸ ATP2A2 P16615 1/20 0.54
▸ ATP2A3 Q93084 1/20 0.54
▸ NR1H4 Q96RI1 6/20 0.54
▸ TSHR P16473 3/20 0.50
▸ TDP1 Q9NUW8 2/20 0.48
▸ HPGD P15428 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11317922 0.86 HSD17B10 (0.50) ALDH1A1ALOX15HSD17B10HTTLMNA
SCHEMBL818330 0.84 HSD17B10 (0.48) ALDH1A1ALOX15HSD17B10HTTLMNA
SCHEMBL8389745 0.83 HSD17B10 (0.48) ALDH1A1ALOX15HSD17B10HTTLMNA
SCHEMBL2789834 0.82 ALDH1A1 (0.54) ALDH1A1ALOX15HSD17B10HTTLMNA
SCHEMBL12804190 0.79 HSD17B10 (0.43) ALDH1A1ALOX15HSD17B10HTTLMNA
SCHEMBL30553151 0.79 ALOX15 (0.44) ALDH1A1ALOX15HSD17B10HTTLMNA
SCHEMBL2437476 0.79 ALOX15 (0.44) ALDH1A1ALOX15HSD17B10HTTLMNA
SCHEMBL11588522 0.79 ALDH1A1 (0.48) ALDH1A1ALOX15HSD17B10HTTLMNA
SCHEMBL8044336 0.79 NR1H4 (0.43) ALDH1A1ALOX15HSD17B10HTTLMNA
SCHEMBL13403326 0.78 MAPK1 (0.46) ALDH1A1ALOX15HSD17B10HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 — — CN claimed
CN-1185240-C Process for one-stage synthesizing substituted diaryl organic metal phosphate SHANGHAI SHENGLIN NEW MATERIAL (CN) 2005-01-19 — — CN claimed
CN-1358728-A Process for one-stage synthesizing substituted diaryl organic metal phosphate SHANGHAI CHENGLIN NEW MATERIAL (CN) 2002-07-17 — — CN claimed
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 — — CN disclosed
CN-119118988-B Method for degrading poly L-lactic acid into L-lactide 苏州大学 2025-04-04 — — CN disclosed
CN-119118988-A Method for degrading poly L-lactic acid into L-lactide 苏州大学 2024-12-13 — — CN disclosed
US-12030853-B2 MASP-2 inhibitors and methods of use OMEROS CORPORATION (US) 2024-07-09 — — US disclosed
US-12030853-B2 MASP-2 inhibitors and methods of use OMEROS CORPORATION (US) 2024-07-09 — — US disclosed
CN-112679635-B Preparation method of supported metallocene catalyst and catalyst prepared by preparation method 中国石油化工股份有限公司 2024-03-26 — — CN disclosed
US-11807641-B2 MASP-2 inhibitors and methods of use OMEROS CORPORATION (US) 2023-11-07 — — US disclosed
US-11807641-B2 MASP-2 inhibitors and methods of use OMEROS CORPORATION (US) 2023-11-07 — — US disclosed
EP-1015518-A1 ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF Ciba SC Holding AG (CH) 2000-07-05 — — EP disclosed
WO-1999052909-A2 DIBENZONAPHTHYRONES AND THEIR USE FOR COLOURING/PIGMENTING HIGH-MOLECULAR-WEIGHT ORGANIC MATERIAL CIBA SPECIALTY CHEMICAL HOLDING INC. (CH) 1999-10-21 — — WO disclosed
WO-1999013007-A1 ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-03-18 — — WO disclosed
EP-0282294-B1 Vinylsilylalkoxy arylbenzotriazole compounds and UV absorbing compositions made therefrom IOLAB CORP (US) 1993-12-01 — — EP disclosed
EP-0283166-B1 2-(2'-HYDROXYPHENYL)-5(6) (ACRYLOYLOXYALKOXY)-BENZOTRIAZOLE AND ULTRAVIOLET ABSORBING POLYMERS THEREFROM IOLAB CORPORATION (US) 1992-01-02 — — EP disclosed
US-4803254-A Vinylsilylalkoxy arylbenzotriazole compounds and UV absorbing compositions made therefrom IOLAB CORPORATION (US) 1989-02-07 — — US disclosed
EP-0283166-A1 2-(2'-Hydroxyphenyl)-5(6) (acryloyloxyalkoxy)-benzotriazole and ultraviolet absorbing polymers therefrom IOLAB CORPORATION (US) 1988-09-21 — — EP disclosed
EP-0282294-A2 Vinylsilylalkoxy arylbenzotriazole compounds and UV absorbing compositions made therefrom IOLAB CORPORATION (US) 1988-09-14 — — EP disclosed
US-3933927-A Phenol transalkylation process ETHYL CORPORATION (US) 1976-01-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807641-B2 MASP-2 inhibitors and methods of use MASP2, METAP2, SPINT2 ALDH1A1 4709/4885ALOX15 3975/4885HSD17B10 3100/4885
US-12030853-B2 MASP-2 inhibitors and methods of use MASP2, METAP2, SPINT2 ALDH1A1 4709/4885ALOX15 3975/4885HSD17B10 3100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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