Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.42 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11166527 | 0.83 | ALDH1A1 (0.60) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| SCHEMBL16117670 | 0.81 | ALDH1A1 (0.67) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| SCHEMBL8389745 | 0.78 | HSD17B10 (0.48) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| SCHEMBL8392107 | 0.78 | CYP3A4 (0.46) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| SCHEMBL6358586 | 0.78 | ALDH1A1 (0.55) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| SCHEMBL19997075 | 0.74 | TSHR (0.41) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| SCHEMBL28787188 | 0.73 | CYP19A1 (0.36) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31409954 | 0.71 | POLB (0.34) | — | |
| SCHEMBL23215872 | 0.70 | SLC6A2 (0.34) | HSD17B10TSHRHPGDLMNAKMT2A | |
| SCHEMBL16736702 | 0.70 | ALOX15 (0.71) | HSD17B10TSHRHPGDALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750607-B1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |