Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334765 | 0.89 | HPGD (0.37) | ALDH1A1MEN1KMT2ACNR2POLB | |
| SCHEMBL8333490 | 0.87 | — | — | |
| SCHEMBL8334475 | 0.86 | CNR1 (0.33) | ALDH1A1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL8341066 | 0.77 | — | — | |
| SCHEMBL8336011 | 0.77 | LMNA (0.33) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL8338167 | 0.77 | HPGD (0.39) | CNR1CNR2POLBLMNA | |
| SCHEMBL8335851 | 0.74 | CNR2 (0.38) | ALDH1A1MEN1KMT2ACNR2CYP1A2 | |
| SCHEMBL8339611 | 0.73 | — | — | |
| SCHEMBL8334832 | 0.73 | CNR2 (0.37) | ALDH1A1MEN1KMT2ACNR2POLB | |
| SCHEMBL8389974 | 0.70 | BCHE (0.31) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |