SCHEMBL1032872

SCHEMBL1032872

Nc1c(F)cc(F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.40
CA2 P00918 6/20 0.40
CA12 O43570 1/20 0.40
CA7 P43166 1/20 0.40
CA13 Q8N1Q1 1/20 0.40
ALDH1A1 P00352 3/20 0.37
LMNA P02545 1/20 0.37
CA4 P22748 2/20 0.35
HDAC1 Q13547 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
CA9 Q16790 3/20 0.33
CA3 P07451 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30952527 1.00 CA1 (0.40) CA1CA2CA12CA7CA13
SCHEMBL8919707 0.88 CA1 (0.40) CA1CA2CA12CA7CA13
SCHEMBL5814455 0.87 CA1 (0.38) CA1CA2CA12CA7CA13
SCHEMBL859273 0.81 CA1 (0.40) CA1CA2CA12CA7CA13
SCHEMBL9150114 0.80 TRPV4 (0.33) CA1CA2CA12CA7CA13
SCHEMBL7073277 0.80 CA1 (0.36) CA1CA2CA12CA7CA13
SCHEMBL7908206 0.80 ALDH1A1 (0.43) CA1CA2CA12CA7CA13
Methylamine SCHEMBL27737724 0.80 CA1 (0.43) CA1CA2CA12CA7CA13
SCHEMBL461597 0.80 CA1 (0.43) CA1CA2CA12CA7CA13
SCHEMBL17104938 0.79 HDAC1 (0.33) CA1CA2ALDH1A1HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118183708-A Method for preparing fluorocarbon material by using fluorine-containing polymer 重庆大学锂电及新材料遂宁研究院 2024-06-14 CN claimed
CN-118183708-A Method for preparing fluorocarbon material by using fluorine-containing polymer 重庆大学锂电及新材料遂宁研究院 2024-06-14 CN disclosed
CN-117929444-A Method, system and related equipment for measuring Hamiltonian amount of sample 深圳量旋科技有限公司 2024-04-26 CN disclosed
US-20230371357-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-16 US disclosed
EP-4273206-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2023-11-08 EP disclosed
CN-106046030-B The application of organic electronic device, dopant with dopant and method for manufacturing dopant 欧司朗OLED股份有限公司 2019-07-16 CN disclosed
US-10158092-B2 Organic electronic component with dopant, use of a dopant and method for the production of the dopant OSRAM OLED GMBH (DE) 2018-12-18 US disclosed
EP-2768926-B1 ORGANIC ELECTRONIC COMPONENT WITH DOPANT, USE OF A DOPANT AND METHOD FOR THE PRODUCTION OF THE DOPANT OSRAM OLED GMBH (DE) 2018-09-19 EP disclosed
US-20180108849-A1 Organic Electronic Component with Dopant, Use of a Dopant and Method for the Production of the Dopant OSRAM OLED GMBH (DE) 2018-04-19 US disclosed
US-9799840-B2 Organic electronic component with dopant, use of a dopant and method for the production of the dopant OSRAM OLED GMBH (DE) 2017-10-24 US disclosed
EP-0035084-B1 SUBSTITUTED N-FLUORPHENYL-N'-HALOGEN BENZOYL UREAS, PROCESS FOR THEIR PREPRATION, COMPOSITIONS CONTAINING THEM AND THEIR USE IN COMBATING PESTS CIBA-GEIGY AG (CH) 1983-08-31 EP disclosed
EP-0026743-B1 POLYSUBSTITUTED DIPHENYL AMINES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1983-05-25 EP disclosed
US-4329518-A INSECTICIDES, ACARICIDES, MITICIDES FMC CORPORATION (US) 1982-05-11 US disclosed
EP-0049977-A1 Insecticidal (1,1'-biphenyl)-3-ylmethyl esters, their production and use and compositions containing them FMC Corporation (US) 1982-04-21 EP disclosed
US-4310548-A Pesticidal N-tetrafluorophenyl-N'-benzoyl ureas CIBA-GEIGY CORPORATION (US) 1982-01-12 US disclosed
EP-0035084-A1 Substituted N-fluorphenyl-N'-halogen benzoyl ureas, process for their prepration, compositions containing them and their use in combating pests CIBA-GEIGY AG (CH) 1981-09-09 EP disclosed
EP-0034945-A2 N-phenylpyrazole derivatives MAY & BAKER LIMITED (GB) 1981-09-02 EP disclosed
EP-0026743-A1 Polysubstituted diphenyl amines, their preparation and their use CIBA-GEIGY AG (CH) 1981-04-08 EP disclosed
EP-0020623-A1 ANALYTICAL PROCESS AND MEANS FOR MEASURING THE AMOUNT OF HYDROGEN PEROXIDE IN AQUEOUS MEDIA AND OF ORGANIC SUBSTRATES GENERATING HYDROGEN PEROXIDE BY ENZYMATIC OXIDATION. BATTELLE MEMORIAL INSTITUTE (CH) 1981-01-07 EP disclosed
WO-1980001081-A1 ANALYTICAL PROCESS AND MEANS FOR MEASURING THE AMOUNT OF HYDROGEN PEROXIDE IN AQUEOUS MEDIA AND OF ORGANIC SUBSTRATES GENERATING HYDROGEN PEROXIDE BY ENZYMATIC OXIDATION BATTELLE MEMORIAL INSTITUTE (CH) 1980-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10158092-B2 Organic electronic component with dopant, use of a dopant and method for the production of the dopant AOC2, DDT, AOC1 CA1 2198/4885CA2 2270/4885CA12 2207/4885
US-20180108849-A1 Organic Electronic Component with Dopant, Use of a Dopant and Method for the Production of the Dopant TYR, DDT, AOC2 CA1 2926/4885CA2 2905/4885CA12 2748/4885
US-20230371357-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, CHRM1, FOXM1 CA1 2274/4885CA2 4073/4885CA12 2600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.